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CN 34-1304/RISSN 1674-3679

Volume 26 Issue 7
Jul.  2022
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ZHANG Xin, WANG Wen-juan, ZHANG Run, YOU Xiao-qing, LI Jian-hong. Relationship between BMI, abdominal obesity and the incidence of acute myocardial infarction in Chinese adults: a prospective study[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(7): 750-755. doi: 10.16462/j.cnki.zhjbkz.2022.07.002
Citation: ZHANG Xin, WANG Wen-juan, ZHANG Run, YOU Xiao-qing, LI Jian-hong. Relationship between BMI, abdominal obesity and the incidence of acute myocardial infarction in Chinese adults: a prospective study[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(7): 750-755. doi: 10.16462/j.cnki.zhjbkz.2022.07.002

Relationship between BMI, abdominal obesity and the incidence of acute myocardial infarction in Chinese adults: a prospective study

doi: 10.16462/j.cnki.zhjbkz.2022.07.002
Funds:

National Key Research and Development Program of China 2018YFC1313904

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  • Corresponding author: LI Jian-hong, E-mail: lijianhong@ncncd.chinacdc.cn
  • Received Date: 2021-12-20
  • Rev Recd Date: 2022-05-13
  • Available Online: 2022-07-19
  • Publish Date: 2022-07-10
  •   Objective  To investigate the relationship between BMI, abdominal obesity and the incidence of acute myocardial infarction (AMI) in Chinese adults.  Methods  Eleven Provinces/Cities were selected from 2010 China Chronic Disease Risk Factor Surveillance, and 60 surveillance sites were selected as follow-up spots. A total of 27 604 participants were followed up from 2016 to 2017. Finally, a total of 26 794 subjects were included in the analysis. The Cox proportional hazard regression model was used to analyze the relationship between BMI, abdominal obesity and the incidence of AMI.  Results  A total of 26 794 subjects were follow-up for an average of 6.0 years. During the follow-up period, of 256 cases of AMI were observed. After adjusting for relevant confounders, compared with normal waist circumference (WC) and BMI < 24 kg/m2 group, the risk of AMI in abdominal obesity and BMI < 24 kg/m2 group increased by 85% (HR=1.85, 95% CI: 1.14-3.01), and the risk of AMI in abdominal obesity group and BMI≥24 kg/m2 group increased by 56% (HR=1.56, 95% CI: 1.11-2.18). However, there was no significant correlation between the risk of AMI and the subjects with normal WC and BMI≥24 kg/m2 (HR=0.85, 95% CI: 0.49-1.47).  Conclusion  Abdominal obesity is an important risk factor for AMI regardless of BMI.
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  • [1]
    Thygesen K, Alpert JS, Jaffe AS, et al. Fourth universal definition of myocardial infarction (2018)[J]. J Am Coll Cardiol, 2018, 72(18): 2231-2264. DOI: 10.1016/j.jacc.2018.08.1038.
    [2]
    Anderson JL, Morrow DA. Acute myocardial infarction[J]. N Engl J Med, 2017, 376(21): 2053-2064. DOI: 10.1056/NEJMra1606915.
    [3]
    中国心血管健康与疾病报告编写组. 中国心血管健康与疾病报告2020概要[J]. 中国循环杂志, 2021, 36(6): 521-545. DOI: 10.3969/j.issn.1000-3614.2021.06.001.

    The Writing Committee of the Report on Cardiovascular Health and Diseases in China. Report on cardiovascular health and diseases burden in China: an updated summary of 2020[J]. Chin Circ J, 2021, 36(6): 521-545. DOI: 10.3969/j.issn.1000-3614.2021.06.001.
    [4]
    Teng RL, Wang H, Sun BC, et al. Interaction between lipoprotein (a) levels and body mass index in first incident acute myocardial infarction[J]. BMC Cardiovasc Disord, 2020, 20(1): 350. DOI: 10.1186/s12872-020-01626-7.
    [5]
    Stegger JG, Schmidt EB, Obel T, et al. Body composition and body fat distribution in relation to later risk of acute myocardial infarction: a Danish follow-up study[J]. Int J Obes (Lond), 2011, 35(11): 1433-1441. DOI: 10.1038/ijo.2010.278.
    [6]
    Dikaiou P, Björck L, Adiels M, et al. Obesity, overweight and risk for cardiovascular disease and mortality in young women[J]. Eur J Prev Cardiol, 2021, 28(12): 1351-1359. DOI: 10.1177/2047487320908983.
    [7]
    Yusuf S, Hawken S, Ounpuu S, et al. Obesity and the risk of myocardial infarction in 27, 000 participants from 52 countries: a case-control study[J]. Lancet, 2005, 366(9497): 1640-1649. DOI: 10.1016/S0140-6736(05)67663-5.
    [8]
    陈春明, 孔灵芝. 中国成人超重和肥胖症预防控制指南[M]. 北京: 人民卫生出版社, 2006.

    Chen CM, Kong LZ. Guidelines for the prevention and control of overweight and obesity in Chinese adults[M]. Beijing: People's Medical Publishing House, 2006.
    [9]
    Parikh NI, Gona P, Larson MG, et al. Long-term trends in myocardial infarction incidence and case fatality in the National Heart, Lung, and Blood Institute's Framingham Heart study[J]. Circulation, 2009, 119(9): 1203-1210. DOI: 10.1161/CIRCULATIONAHA.108.825364.
    [10]
    中国肥胖问题工作组. 中国成人超重和肥胖症预防与控制指南(节录)[J]. 营养学报, 2004, 26(1): 1-4. DOI: 10.13325/j.cnki.acta.nutr.sin.2004.01.001.

    China Working Group on Obesity. Guidelines for the prevention and control of overweight and obesity in Chinese adults (excerpt)[J]. Acta Nutrimenta Sinica, 2004, 26(1): 1-4. DOI: 10.13325/j.cnki.acta.nutr.sin.2004.01.001.
    [11]
    Marbou WJT, Kuete V. Prevalence of metabolic syndrome and its components in bamboutos division's adults, west region of Cameroon[J]. Biomed Res Int, 2019, 2019: 9676984. DOI: 10.1155/2019/9676984.
    [12]
    Wadolowska L, Hamulka J, Kowalkowska J, et al. Changes in sedentary and active lifestyle, diet quality and body composition nine months after an education program in Polish students aged 11-12 years: report from the ABC of healthy eating study[J]. Nutrients, 2019, 11(2): E331. DOI: 10.3390/nu11020331.
    [13]
    Chatelan A, Castetbon K, Pasquier J, et al. Association between breakfast composition and abdominal obesity in the Swiss adult population eating breakfast regularly[J]. Int J Behav Nutr Phys Act, 2018, 15(1): 115. DOI: 10.1186/s12966-018-0752-7.
    [14]
    Pan XF, Wang LW, Pan A. Epidemiology and determinants of obesity in China[J]. Lancet Diabetes Endocrinol, 2021, 9(6): 373-392. DOI: 10.1016/S2213-8587(21)00045-0.
    [15]
    Kim DH, Nam GE, Han K, et al. Variabilities in weight and waist circumference and risk of myocardial infarction, stroke, and mortality: a nationwide cohort study[J]. Endocrinol Metab (Seoul), 2020, 35(4): 933-942. DOI: 10.3803/EnM.2020.871.
    [16]
    Sharma S, Batsis JA, Coutinho T, et al. Normal-weight central obesity and mortality risk in older adults with coronary artery disease[J]. Mayo Clin Proc, 2016, 91(3): 343-351. DOI: 10.1016/j.mayocp.2015.12.007.
    [17]
    Mourmoura E, Chaté V, Couturier K, et al. Body adiposity dictates different mechanisms of increased coronary reactivity related to improved in vivo cardiac function[J]. Cardiovasc Diabetol, 2014, 13: 54. DOI: 10.1186/1475-2840-13-54.
    [18]
    Piché ME, Tchernof A, Després JP. Obesity phenotypes, diabetes, and cardiovascular diseases[J]. Circ Res, 2020, 126(11): 1477-1500. DOI: 10.1161/CIRCRESAHA.120.316101.
    [19]
    Mørkedal B, Vatten LJ, Romundstad PR, et al. Risk of myocardial infarction and heart failure among metabolically healthy but obese individuals: hunt (Nord-Trøndelag Health Study), Norway[J]. J Am Coll Cardiol, 2014, 63(11): 1071-1078. DOI: 10.1016/j.jacc.2013.11.035.
    [20]
    Emerging Risk Factors Collaboration, Wormser D, Kaptoge S, et al. Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies[J]. Lancet, 2011, 377(9771): 1085-1095. DOI: 10.1016/S0140-6736(11)60105-0.
    [21]
    Kachur S, Lavie CJ, de Schutter A, et al. Obesity and cardiovascular diseases[J]. Minerva Med, 2017, 108(3): 212-228. DOI: 10.23736/S0026-4806.17.05022-4.
    [22]
    Elagizi A, Kachur S, Carbone S, et al. A review of obesity, physical activity, and cardiovascular disease[J]. Curr Obes Rep, 2020, 9(4): 571-581. DOI: 10.1007/s13679-020-00403-z.
    [23]
    Zhang P, Wang R, Gao CS, et al. Prevalence of central obesity among adults with normal BMI and its association with metabolic diseases in northeast China[J]. PLoS One, 2016, 11(7): e0160402. DOI: 10.1371/journal.pone.0160402.
    [24]
    Artham SM, Lavie CJ, Milani RV, et al. Value of weight reduction in patients with cardiovascular disease[J]. Curr Treat Options Cardiovasc Med, 2010, 12(1): 21-35. DOI: 10.1007/s11936-009-0056-y.
    [25]
    Ortega FB, Lavie CJ, Blair SN. Obesity and cardiovascular disease[J]. Circ Res, 2016, 118(11): 1752-1770. DOI: 10.1161/CIRCRESAHA.115.306883.
    [26]
    Swift DL, Johannsen NM, Lavie CJ, et al. Effects of clinically significant weight loss with exercise training on insulin resistance and cardiometabolic adaptations[J]. Obesity (Silver Spring), 2016, 24(4): 812-819. DOI: 10.1002/oby.21404.
    [27]
    Wells JCK. Commentary: The paradox of body mass index in obesity assessment: not a good index of adiposity, but not a bad index of cardio-metabolic risk[J]. Int J Epidemiol, 2014, 43(3): 672-674. DOI: 10.1093/ije/dyu060.
    [28]
    Taylor AE, Ebrahim S, Ben-Shlomo Y, et al. Comparison of the associations of body mass index and measures of central adiposity and fat mass with coronary heart disease, diabetes, and all-cause mortality: a study using data from 4 UK cohorts[J]. Am J Clin Nutr, 2010, 91(3): 547-556. DOI: 10.3945/ajcn.2009.28757.
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