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CN 34-1304/RISSN 1674-3679

Volume 27 Issue 7
Jul.  2023
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YIN Daogen, HE Zhen, ZENG Xiaohui, DUAN Xueyan, LIAO Xiaobing, LU Wanke. Study on the risk factors of allergic diseases in infants aged 0-36 months in Longhua District, Shenzhen[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2023, 27(7): 821-826. doi: 10.16462/j.cnki.zhjbkz.2023.07.013
Citation: YIN Daogen, HE Zhen, ZENG Xiaohui, DUAN Xueyan, LIAO Xiaobing, LU Wanke. Study on the risk factors of allergic diseases in infants aged 0-36 months in Longhua District, Shenzhen[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2023, 27(7): 821-826. doi: 10.16462/j.cnki.zhjbkz.2023.07.013

Study on the risk factors of allergic diseases in infants aged 0-36 months in Longhua District, Shenzhen

doi: 10.16462/j.cnki.zhjbkz.2023.07.013
Funds:

Medical Research Projects of Longhua District, Shenzhen 2020167

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  • Corresponding author: DUAN Xueyan, E-mail: 1979805961@qq.com
  • Received Date: 2021-04-24
  • Rev Recd Date: 2021-09-07
  • Available Online: 2023-08-08
  • Publish Date: 2023-07-10
  •   Objective  The study aims to analyze the various risk factors associated with allergic diseases in infants aged 0-36 months, thereby providing a theoretical framework for preventive measures against such conditions.  Methods  Parents of children aged 0-36 months who attended the community health service institutions for routine physical examinations in L District, Shenzhen, were selected for this study.Data on allergic diseases were collected through a structured questionnaire survey.Subsequent analysis was performed using Chi-square, t-test, and binomial logistic regression to assess both risk and protective factors of allergic diseases.  Results  A total of 399 children were collected, including 209 boys and 190 girls.The allergic group comprised 80 children (20.05%) who had allergic diseases, while the normal group consisted of 319 children (79.95%) without any allergic conditions.The univariate and multivariate analyses revealed the father's allergic history (OR=4.009, 95% CI: 1.618-9.930), house decoration (OR=5.702, 95% CI: 1.247-26.075), gestational disease history (OR=2.022, 95% CI: 1.022-4.000), probiotics use in infants (OR=2.214, 95% CI: 1.201-4.081), and high stress during pregnancy (OR=5.296, 95% CI: 1.298-21.616) were the risk factors of allergic diseases in infants (all P < 0.05).Conversely, probiotics supplementation during pregnancy (OR=0.427, 95% CI: 0.210-0.867) served as a protective factor against these conditions in infants (P < 0.05).  Conclusions  The results indicate that factors such as the father's allergic history, indoor housing renovations, a history of gestational diseases, the usage of probiotics in infants, and high levels of stress during pregnancy may increase the susceptibility of infants to allergic diseases.However, the administration of probiotics during pregnancy may serve as a protective factor against the onset of these allergic conditions in infants.
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