晚餐-睡眠间隔时间和晚餐后散步与胃癌关系的病例对照研究

张曦; 许乐; 戴嘉喜; 林仁琴; 田芳曦; 梁冰; 郭谊楠

doi:10.16462/j.cnki.zhjbkz.2016.10.009

晚餐-睡眠间隔时间和晚餐后散步与胃癌关系的病例对照研究

doi: 10.16462/j.cnki.zhjbkz.2016.10.009

1. 福建医科大学护理学院外科教研室, 福建福州 350108;
2. 福建医科大学附属协和临床医学院护理教研室, 福建福州 350001

基金项目:

国家临床重点专科建设项目（国卫办医函[2013]544号）

详细信息

作者简介:
张曦(1990-),女,湖南怀化人,在读硕士研究生。主要研究方向:胃癌病因学研究。

中图分类号: R735.2;R181.2
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- 被引次数: 0
出版历程
- 收稿日期: 2016-04-06
- 修回日期: 2016-07-27

A case-control study on relationship between dinner-to-bed time, post-dinner walk and gastric cancer

1. Department of Surgery, School of Nursing, Fujian Medical University, Fuzhou 350108, China;
2. Department of Nursing, Fujian Medical University Union Hospital, Fuzhou 350001, China

摘要

摘要: 目的探讨晚餐-睡眠间隔时间和晚餐后散步与胃癌的关系。方法收集胃癌病例428例，同期选取年龄、性别匹配的健康对照441例。通过问卷调查研究对象的人口学特征、晚餐-睡眠间隔时间和晚餐后散步等生活行为习惯。结果较短的晚餐-睡眠间隔时间可增加胃癌的发病风险（OR_adjusted=2.858，95% CI：1.893~4.314），晚餐后无散步相比散步胃癌的发生风险增加（OR=2.909，95% CI：2.037~4.153）。较短的晚餐-睡眠间隔时间且餐后无散步患胃癌的危险性比较长间隔时间且散步的大（OR=6.427，95% CI：3.964~10.419）。晚餐-睡眠时间与晚餐后散步乘积项（OR_adjusted=1.572，95% CI：1.361~3.769），交互作用系数为3.273。结论较短的晚餐-睡眠间隔时间和晚餐后无散步与胃癌发生具有关联且两者之间的交互作用可增加胃癌的发病风险。
- 胃肿瘤 /
- 问卷调查 /
- 病例对照研究
Abstract: Objective To investigate the relationship between dinner-to-bed time, post-dinner walk and gastric cancer (GC). Methods 428 newly diagnosed GC patients and 441 age and gender matched healthy controls were recruited from local residents. A self-designed questionnaire was used to collect information including basic demographic characteristics, dinner-to-bed time interval and post-dinner walk etc. Results Shorter dinner-to-bed time was significantly associated with an increased risk of GC(OR_adjusted=2.858,95% CI:1.893-4.314). Non post-dinner walk was associated with increased risk of GC as compared with post-dinner walk(OR=2.909, 95% CI:2.037-4.153). The risk of GC individuals with shorter dinner-to-bed time and no post-dinner walk caused higher risk than those with longer dinner-to-bed time and post-dinner walk(OR=6.427, 95% CI:3.964-10.419).The product of dinner-to-bed time and post-dinner walk was (OR_adjusted=1.572, 95% CI:1.361-3.769)and the interaction index was 3.273. Conclusions The study suggests that both shorter dinner-to-bed time and no post-dinner walk are strong risk factors of GC, also the interaction of dinner-to-bed time and post-dinner walk significantly increase the risk of GC.
- Stomach neoplasms /
- Questionnaires /
- Case-control studies

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参考文献(18)

Global Burden of Disease Cancer Collaboration, Fitzmaurice C, Dicker D, et al. The Global Burden of Cancer 2013[J]. JAMA Oncol, 2015,1(4):505-527.

Correa P. Human gastric carcinogenesis: a multistep and multi-factorial process: First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention[J]. Cancer Res, 1992,52(24):6735-6740.

Brenner H, Rothenbacher D, Ardnt V. Epidemiology of stomach cancer[J]. Methods Mol Biol, 2009,472:467-477.

沈孝兵,张娇,浦跃朴,等. 胃癌的环境与遗传危险因素及归因危险度分析[J]. 中国公共卫生, 2005,21(1):1-3.

Fujiwara Y, Machiada A, Watanabe Y, et al. Association between dinner-to-bed Time and gastro-esophageal reflux disease[J]. Am J Gastroenterol, 2005,100(12):2633- 2636.

Piesman M, Hwang I, Maydonovitch C, et al. Nocturnal reflux episodes Followingthe administration of standardized meal. Dose timing matter?[J]. Am J Gastroenterol, 2007,102(10):2128-2134.

Song Q, Liu H, Wang J, et al. Dinner-to-bed time and post-dinner walk: new potential independent factors in esophageal cancer development[J]. J Cancer Res Clin Oncol, 2014,140(5):817-821.

Karim S, Jafri W, Faryal A, et al. Regular post dinner walk; can be a useful lifestyle modification for gastro-esophageal reflux[J]. J Pak Med Assoc, 2011,61(6):526-630.

Parent MÉ, Rousseau MC, El-Zein M. Occupational and recreational physical activity during adult life and the risk of cancer among men[J]. Cancer Epidemiol, 2011,35(2):151-159.

纪雪梅,孙凌,何忠时,等. 吸烟饮酒作为低发区鼻咽癌致病因素的分析[J].中华疾病控制杂志, 2010,14(5):393-396.

Lin S, Wang X, Huang C, et al. Consumption of salted meat and its interactions with alcohol drinking and tobacco smoking on esophageal squamous-cell carcinoma[J]. Int J Cancer, 2015,137(3):582-589.

胡祥炬,林曙光,钟文玲,等. 福建省5个国家疾病监测点成人超重肥胖的影响因素分析[J]. 中华疾病控制杂志, 2013,17(1):20-23.

Behrens G, Jochem C, Keimling M, et al. The association between physical activity and activity and gastroesophageal cancer: systematic review and meta-analysis[J]. Eur J Epidemiol, 2014,29(3):151-170.

Znaor A, Brennan P, Gajalakshmi V, et al. Independent and combined effects of tobacco smoking, chewing and alcohol drinking on the risk of oral, pharyng-eal and esophageal cancers in Indian men[J]. Int J Cancer, 2003,105(5):681-686.

Dodds WJ, Dent J, Hogan WJ, et al. Mechanisms of gastroesophageal reflux in patients with reflux esophagitis[J]. N Engl J Med, 1982,307(25):1547-1552.

Collins PJ, Horowitz M, Chatterton BE. Proximal distal and total stomach emptying of a digestible solid meal in normal subjects[J]. Br J Radiol, 1988,61(721):12-18.

Avidan B, Sonnenberg A, Schnell TG, et al. Walking and chewing reduce postprandial acid reflux[J]. Aliment Pharmacol Ther, 2001,15(2):151-155.

Bradley RL, Jeon JY, Liu FF, et al. Voluntary exercise improves insulin sensitivity and adipose tissue inflammation in diet-induced obese mice[J]. Am J Physiol Endocrinol Metab, 2008,295(3):E586-594.

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