Abstract: Objective To observe the prevalence rate of cyberbullying among adolescents in Anhui province, and to analyze the relationship between cyberbullying and suicide-related behavior, to provide the basis for intervention of cyberbullying and suicide-related behavior. Methods 10 574 students were selected from 5 vocational colleges by stratified cluster random sampling in Anhui province, to measure the situation of cyberbullying and suicide-related behavior, analyze the relationship between cyberbullying and suicide-related behavior. Results 10 158 valid questionnaires were obtained, 3.3% of study subjects were victims of cyberbullying. Prevalence rates of suicide idea, suicide plan and suicide attempt were 5.6%, 3.5% and 1.8%, respectively. Logistic regression analysis results showed that being cyberbullied was the risk factor of suicidal ideation, suicidal plan and attempted suicide in both sexes (all P<0.05). Conclusions Cyberbulling victimization is common among adolescents, and cyberbullying has a close relationship with suicide-related behavior, these should be paird more attention.