摘要:
目的 评价宫颈癌患者生命质量，并探讨其影响因素。方法 采用癌症治疗功能评价系统中的宫颈癌量表（functional assessment of cancer therapy-cervix v4.0，FACT-Cx（V4.0））中文版对120例宫颈癌患者进行调查。采用t检验、方差分析、多重线性回归等方法进行统计分析。结果 宫颈癌患者健康相关生命质量总分为（104.88±19.51）分，生理状况、社会/家庭状况、情感状况、功能状况、附加关注各维度得分分别为（20.41±5.46）分、（17.17±6.10）分、（15.73±5.06）分、（13.34±5.83）分、（38.23±6.26）分。多因素分析结果中，生理状况的影响因素为婚姻状况、临床分期，社会/家庭状况的影响因素为婚姻状况，情感状况的影响因素为文化程度、临床分期，功能状况、附加关注及量表总分的影响因素均为婚姻状况、文化程度及临床分期。结论 影响宫颈癌患者的生命质量的影响因素有多种，针对患者的实际情况，给与患者鼓励及精神支持，缓解患者症状、降低治疗副反应对提高宫颈癌患者生命质量有重要意义。
Abstract:
Objective To evaluate the health-related quality of life (HRQOL) and its influencing factors in patients with cervical cancer. Methods 120 inpatients with cervical cancer at Yunnan Tumor Hospital were investigated by functional assessment of cancer therapy-cervix (FACT-Cx), t-test, analysis of variance and multiple linear regression were used to analyze factors influencing the HRQOL. Results The total HRQOL score of patients was (104.88±19.51), and the domain scores of physical well-being (PWB), social/family well-being (SWB), emotional well-being (EWB), functional well-being (FWB), cervical cancer subscale (CxS) were (20.41±5.46), (17.17±6.10), (15.73±5.06), (13.34±5.83), (38.23±6.26), respectively. Based on multiple linear regression,the influencing factors of PWB were marital status and clinical stages, the influencing factor of SWB was marital status, the influencing factors of EWB were education levels and clinical stages, the influencing factors of FWB, CxS and total score were all marital status, clinical stages and education levels. Conclusions The HRQOL scores were influenced by a number of factors and it is significant to improve HRQOL in patients with cervical cancer by relieving symptoms and reducing treatment side effects according to patients' specialty, also psychological support and encouragement was essential.
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