规律服药的糖尿病患者体力活动水平与糖化血红蛋白控制状况的关系

金玲玲; 马雨杨; 叶青; 秦真真; 董易苹; 王志勇; 徐斐

doi:10.16462/j.cnki.zhjbkz.2019.05.017

规律服药的糖尿病患者体力活动水平与糖化血红蛋白控制状况的关系

doi: 10.16462/j.cnki.zhjbkz.2019.05.017

金玲玲¹,
马雨杨¹,
叶青²,
秦真真²,
董易苹³,
王志勇²,
徐斐^{1, 2, ,}

1.
210029 南京, 南京医科大学公共卫生学院流行病学系
2.
210003 南京, 南京市疾病预防控制中心慢病防制科
3.
210009 南京, 东南大学公共卫生学院

基金项目:

2015年度南京市科技发展计划项目 201503054

详细信息

通讯作者:
徐斐, E-mail: frankxufei@163.com

中图分类号: R181;R587.1
计量
- 文章访问数: 399
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- 被引次数: 0
出版历程
- 收稿日期: 2018-12-13
- 修回日期: 2019-02-19
- 刊出日期: 2019-05-10

Association between physical activity and glycemic control among type 2 diabetic patients with a good compliance level

1.
Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing 210029, China
2.
Department of Chronic Disease Prevention, Nanjing Municipal Center for Disease Control and Prevention, Nanjing 210003, China
3.
School of Public Health, Southeast University, Nanjing 210009, China

Funds:

Nanjing Municipal Science and Technique Foundation 201503054

More Information

Corresponding author: XV Fei, E-mail: frankxufei@163.com

摘要

摘要: 目的了解遵医嘱规律服药的糖尿病患者体力活动水平与糖化血红蛋白控制状况之间的关系，为糖尿病患者的健康干预提供依据。方法于2014-2016年间收集南京化工园区5家社区卫生服务中心纳入管理的遵医嘱规律服药的2型糖尿病患者作为研究对象。采用单因素和多因素非条件Logistic回归模型，研究不同性别2型糖尿病患者体力活动水平与糖化血红蛋白的关系。结果本研究纳入分析1 272人，其中男596例(46.9%)，女676例(53.1%)，平均年龄为(64.63±9.04)岁。按性别分层分析结果显示，体力活动水平充足的男性糖尿病患者的糖化血红蛋白达标率为体力活动水平不充足男性患者的2.11倍(95%CI：1.17~3.78，P=0.013)，女性患者中二者差异无统计学意义。结论加强遵医嘱规律服药的糖尿病患者体力活动水平可以帮助血糖的控制。
- 规律服药 /
- 体力活动水平 /
- 糖化血红蛋白 /
- 2型糖尿病
Abstract: Objective To examine the relationship between physical activity and glycemic control among type 2 diabetic patients with a good compliance level in China. Methods A total of 1 272 patients diagnosed with type 2 diabetes with a good compliance level were recruited from five community health centers in Nanjing Chemical Industry Administrative Zone from 2014 to 2016. Logistic regression models were used to examine the relationship between physical activity and glycemic control. Results In this cross-sectional study, 1 272 type 2 diabetic patients (596 men and 676 women) were recruited. The participants' mean (standard deviation, SD) age was (64.63±9.04) years old. Male participants who achieved sufficient physical activity had the odds ratio (OR) of 2.11 (95%CI: 1.17-3.18, P=0.013) for a tight glycemic control compared to their counterparts who had sufficient physical activity, after controling for the potential confounders, no significant association between physical activity and glycemic control status existed in women. Conclusions Physical activity is positively associated with glycemic control among male type 2 diabetic patients who had a good compliance level in Nanjing. Specific physical activity interventions should be implemented to type 2 diabetic patients.
- Medication under prescription /
- Physical activity /
- Glycemic control /
- Type 2 diabetic patients

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表 1 体力活动水平是否充足的社会人口学分布[n(%)]

Table 1. Comparison of the prevalence of meeting the physical activity recommendations with different social demographic characteristics[n(%)]

特征	体力活动水平		t/χ²值	P值
特征	不充足	充足	t/χ²值	P值
总人群	193(15.2)	1 079(84.8)	1.74	0.083
性别
男	83(13.9)	513(86.1)	1.35	0.245
女	110(16.3)	566(83.7)
婚姻状况
未婚或其他	15(16.9)	74(83.1)	0.21	0.647
已婚	178(15.0)	1 005(85.0)
受教育程度
初中及以下	150(16.9)	740(83.1)	7.87	0.020
高中或中专	38(12.3)	271(87.7)
大专及以上	5(6.80)	68(93.2)
月收入水平(元)
＜2000	81(19.2)	340(80.8)	8.88	0.012
2000~	43(14.7)	250(85.3)
≥3000	69(12.4)	489(87.6)
吸烟
否	148(14.9)	844(85.1)	0.23	0.635
是	45(16.1)	235(83.9)
BMI(kg/m²)
＜24	74(14.8)	426(85.2)	0.09	0.765
≥24	119(15.4)	653(84.6)

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表 2 糖化血红蛋白是否达标的社会人口学分布[n(%)]

Table 2. Comparison of the prevalence of meeting the HbA1c (hemoglobin A1c) target with different social demographic characteristics[n(%)]

特征	糖化血红蛋白		t/χ²值	P值
特征	不达标	达标	t/χ²值	P值
总人群	769(60.5)	503(39.5)	-0.87	0.385
性别
男	358(60.1)	238(39.9)	0.07	0.790
女	411(60.8)	265(39.2)
婚姻状况
未婚及其他	55(61.8)	34(38.2)	0.07	0.788
已婚	714(60.4)	469(39.6)
受教育程度
初中及以下	561(63.0)	329(37.0)	8.77	0.012
高中或中专	171(55.3)	138(44.7)
大专及以上	37(50.7)	36(49.3)
月收入水平(元)
＜2000	271(64.4)	150(35.6)	4.31	0.116
2000~	175(59.7)	118(40.3)
≥3000	323(57.9)	235(42.1)
吸烟
否	595(60.0)	397(40.0)	0.43	0.513
是	174(62.1)	106(37.9)
BMI(kg/m²)
＜24	278(55.6)	222(44.4)	8.13	0.004
≥24	491(63.6)	281(36.4)

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表 3 不同性别体力活动水平与糖化血红蛋白控制情况

Table 3. Logistic regression analysis of physical activity and glycemic control status stratified by gender

体力活动水平	人数(人)	达标人数(人)	达标率(%)	OR(95%CI)值	OR(95%CI)值^a
总体
达标	1 079	440	40.8	1.00	1.00
不达标	193	63	32.6	1.42(1.03~1.97)	1.57(1.09~2.28)
男性
达标	513	216	42.1	1.00	1.00
不达标	83	22	26.5	2.02(1.20~3.39)	2.11(1.17~3.78)
女性
达标	566	225	39.8	1.00	1.00
不达标	110	40	36.4	1.16(0.76~1.76)	1.16(0.70~1.93)
注：^a调整了年龄、性别、婚姻状况、受教育程度、收入、医疗保障、吸烟、肉类频次、病程、糖尿病家族史、BMI、体力活动等混杂因素。

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