2014―2023年福建省戊型病毒性肝炎流行趋势和时空聚集性

张海荣; 林志强; 吴瑞红; 黄丽芳

doi:10.16462/j.cnki.zhjbkz.2024.11.019

2014―2023年福建省戊型病毒性肝炎流行趋势和时空聚集性

doi: 10.16462/j.cnki.zhjbkz.2024.11.019

福建省疾病预防控制中心免疫规划所，福州 350012

基金项目:

福建省卫生健康科技计划项目 2020GGB020

福建省科技创新平台建设项目 2019Y2001

详细信息

通讯作者:
黄丽芳，E-mail: huanglf351@126.com

中图分类号: R512.6; R181.3
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- 文章访问数: 75
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- 被引次数: 0
出版历程
- 收稿日期: 2024-07-03
- 修回日期: 2024-10-15
- 网络出版日期: 2024-12-23
- 刊出日期: 2024-11-10

Epidemiological trends and spatiotemporal clustering of hepatitis E in Fujian Province, 2014-2023

Department of Immunization Program, Fujian Provincial Center for Disease Control and Prevention, Fuzhou 350012, China

Funds:

Health Science and Technology Program in Fujian Province 2020GGB020

Construction of Fujian Provincial Scientific and Technological Innovation Platform 2019Y2001

More Information

Corresponding author: HUANG Lifang, E-mail: huanglf351@126.com

摘要

摘要: 目的分析福建省戊型病毒性肝炎(简称戊肝)的流行趋势和时空聚集性。方法通过中国疾病预防控制信息系统收集2014―2023年福建省戊肝报告发病数据，运用Joinpoint 5.1.0.0模型描述报告发病率的变化趋势，使用SaTScan V9.5软件进行时空扫描分析。结果 2014―2023年福建省共报告戊肝病例8 108例，年均报告发病率为2.05/10万，2014―2020年呈下降趋势(APC=-7.41%, 95% CI: -22.09%~2.25%, P=0.009)，2020―2023年呈上升趋势(APC=15.95%, 95% CI: 0.94%~42.43%, P=0.034)。戊肝主要流行季节在冬春季，男性戊肝报告发病率高于女性(χ² =583.42, P < 0.001)，报告发病率随年龄的增长总体呈上升趋势(趋势χ² =4 607.00, P < 0.001)。时空扫描分析发现7类戊肝空间聚集区域。结论 2014―2023年福建省戊肝报告发病率呈先下降后上升趋势，中老年男性为主要发病人群，发病分布存在时空聚集性，需加强高危人群和热点地区的戊肝监测和防控。
- 戊型病毒性肝炎 /
- 流行趋势 /
- 时空聚集性
Abstract: Objective To analyze the epidemic trend and spatiotemporal clustering of hepatitis E in Fujian Province. Methods The reported incidence data of hepatitis E in Fujian Province from 2014 to 2023 were collected through the China information system for disease control and prevention. The change trend of the reported incidence rate was described using the Joinpoint 5.1.0.0 model. Spatiotemporal scanning analysis was performed using SaTScan V9.5 software. Results A total of 8108 cases of hepatitis E were reported in Fujian Province during 2014-2023, for an average annual reported incidence of 2.05 per 100 000. there was a downward trend (APC=-7.41%, 95% CI: -22.09%-2.25%, P=0.009), while from 2020 to 2023, there was an upward trend (APC=15.95%, 95% CI: 0.94%-42.43%, P=0.034). The main epidemic season was winter and spring. The reported incidence rate of hepatitis E in men was higher than that in women (χ² =583.42, P < 0.001), and the reported incidence rate showed an over all upward trend with the increase of age (χ² =4 607.00, P < 0.001). The spatiotemporal scan analysis has revealed seven types of spatial clustering areas for hepatitis E. Conclusions From 2014 to 2023, the reported incidence rate of hepatitis E in Fujian Province showed a downward trend and then an upward trend middle aged and elderly men were the main affected population, and the incidence was spatiotemporal clustering. It was necessary to strengthen the monitoring of hepatitis E in high-risk groups and hot spots.
- Viral hepatitis E /
- Popular trends /
- Spatiotemporal clustering

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图 1 2014―2023年福建省戊型病毒性肝炎报告分年龄报告发病数及发病率趋势

Figure 1. Trends in the number of reported cases and incidence rate of hepatitis E by age group in Fujian Province from 2014 to 2023

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表 1 2014―2023年福建省戊型病毒性肝炎报告发病率时空扫描分析

Table 1. Spatiotemporal scan analysis results of incidence rate of hepatitis E in Fujian province, 2014-2023

聚集类型 Type of cluster	聚集城市 [县(区)数/个] Aggregated cities (the number of counties districts/case)	半径 Radius /km	聚集时间/ 年 Gathering time/ year	报告病例数 Number of cases	期望病例数 Expected cases	波及人口数/万 Population /10 000	RR值 value	LLR值 value	P值 value
一类 Class Ⅰ	龙岩市(1) Longyan City (1)	0	2015―2016	124	9.73	24.52	12.93	202.17	< 0.001
二类 Class Ⅱ	三明市(8)、南平市(5)Sanming City (8), Nanping City (5)	105.05	2014―2015	328	115.47	305.82	2.92	132.77	< 0.001
三类 Class Ⅲ	福州市(3)、宁德市(7)Fuzhou City (3), Ningde City (7)	89.31	2014―2015	292	128.59	365.17	2.32	77.76	< 0.001
四类 Class Ⅳ	厦门市(1) Xiamen City (1)	9.88	2018―2019	96	41.75	102.87	2.32	25.87	< 0.001
五类 ClassⅤ	泉州市(1)Quanzhou City (1)	0	2022―2023	41	16.43	38.47	2.50	12.96	0.002
六类 ClassⅥ	平潭综合实验区(1)Pingtan Comprehensive Experimental Zone(1)	0	2022―2022	55	7.77	41.65	7.12	60.53	< 0.001
七类 ClassⅦ	福州市(7)、莆田市(1)Fuzhou City (7), Putian City (1)	48.82	2022―2023	500	217.59	550.46	2.38	138.75	< 0.001

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参考文献(7)

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