Effects of the hepatitis B immune globulin on the antenatal interruption of pregnant women infected with hepatitis B virus

LI Dong-liang; TANG Ren-shu; LIU Zhen-wu; LIU Xu-xiang; WANG Bei; WANG Xiao-ping

doi:10.16462/j.cnki.zhjbkz.2016.09.006

Volume 20 Issue 9

Sep. 2016

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Article Navigation > CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION > 2016 > 20(9): 885-887,892

LI Dong-liang, TANG Ren-shu, LIU Zhen-wu, LIU Xu-xiang, WANG Bei, WANG Xiao-ping. Effects of the hepatitis B immune globulin on the antenatal interruption of pregnant women infected with hepatitis B virus[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(9): 885-887,892. doi: 10.16462/j.cnki.zhjbkz.2016.09.006

Citation:

LI Dong-liang, TANG Ren-shu, LIU Zhen-wu, LIU Xu-xiang, WANG Bei, WANG Xiao-ping. Effects of the hepatitis B immune globulin on the antenatal interruption of pregnant women infected with hepatitis B virus[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(9): 885-887,892. doi: 10.16462/j.cnki.zhjbkz.2016.09.006

Citation:

LI Dong-liang, TANG Ren-shu, LIU Zhen-wu, LIU Xu-xiang, WANG Bei, WANG Xiao-ping. Effects of the hepatitis B immune globulin on the antenatal interruption of pregnant women infected with hepatitis B virus[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(9): 885-887,892. doi: 10.16462/j.cnki.zhjbkz.2016.09.006

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Effects of the hepatitis B immune globulin on the antenatal interruption of pregnant women infected with hepatitis B virus

doi: 10.16462/j.cnki.zhjbkz.2016.09.006

Department of Immunization Programs, Hefei Center for Disease Prevention and Control, Hefei 230000, China

Received Date: 2015-12-24
Rev Recd Date: 2016-04-16

Abstract

Abstract

Objective To analyze the results of the mother-to-infant transmission interrupting of hepatitis B virus (HBV) in Hefei and evaluate the validity of current antenatal interruption method, so as to provide reasonable basis for the interrupting. Methods This study was established on the monitoring system of the pregnant women infected with HBV in Hefei. The pregnant women infected with HBV were grouped according to the risk of HBV-DNA titers and condition of antenatal injection of hepatitis B immune globulin (HBIg). All their infants were investigated five makers of hepatitis B at one year old. And if the hepatitis B surface antigen (HBsAg) was positive, it came that the interrupting failed. The HBV-DNA titers of the pregnant women injected with HBIg were monitored both before and after injection, so as to study the effect of HBIg on the mother-to-infant transmission antenatal interruption. Results The total cases of pregnant women with HBV were 395 from 2009 to 2013. The positive rate of control group was 2.74% and the treatment group was 3.88%. The difference between two rates was not statistically significant by Chi-square test and also the titer change between before and after injection. Conclusions Effect of HBIg on the antenatal interruption of pregnant women infected with HBV should be further studied.
- Hepatitis,
- Pregnant women,
- Comp study

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References(20)

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