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CN 34-1304/RISSN 1674-3679

ZHU Xiao-yan, HUANG Tao, WANG Guo-yong, HUANG Peng-xiang, ZHANG Na, LIAO Mei-zhen, TAO Xiao-run, KANG Dian-min. Effectiveness of antiviral treatment among HIV/AIDS patients aged above 50 years in Shandong Province[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(12): 1199-1202,1207. doi: 10.16462/j.cnki.zhjbkz.2016.12.004
Citation: ZHU Xiao-yan, HUANG Tao, WANG Guo-yong, HUANG Peng-xiang, ZHANG Na, LIAO Mei-zhen, TAO Xiao-run, KANG Dian-min. Effectiveness of antiviral treatment among HIV/AIDS patients aged above 50 years in Shandong Province[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(12): 1199-1202,1207. doi: 10.16462/j.cnki.zhjbkz.2016.12.004

Effectiveness of antiviral treatment among HIV/AIDS patients aged above 50 years in Shandong Province

doi: 10.16462/j.cnki.zhjbkz.2016.12.004
  • Received Date: 2016-07-11
  • Rev Recd Date: 2016-10-13
  • Objective To analyze the results of antiretroviral therapy among HIV/AIDS patients aged above 50 years in Shandong Province. Methods A face-to-face interview was conducted to collect baseline and after treatment data among HIV/AIDS patients aged above 50 years who started antiretroviral therapy in Shandong province during 2003 to 2014. The CD4+T cell count and viral load were analyzed to evaluate the effect of antiretroviral therapy. Results Of the 322 patients, 76.7% were male and 23.3% were female. The average age was (56.9±6.4) years old. 63.4% were married or cohabiting. Heterosexual transmission was the major transmission route, accounting for 54.3%.The median of CD4+ T cell count was 194.0 (83.5-301.0) on baseline, and there was significant difference in CD4+ T cell count among HIV/AIDS patients by different transmission route (H=14.200,P=0.003). CD4+ T cell count of different time points after treatment showed differences compared with the baseline data(all P<0.001).The Logistic analysis showed that gender and opportunistic infections status before treatment were the influencing factor of therapeutic effectiveness (all P<0.05). There was no significant difference among the proportion of complete inhibition of virus at different time periods (χ2=2.093, P=0.719). Conclusions The antiretroviral therapy can effectively improve the body immunity, reduce viral load of HIV/AIDS in patients aged above 50 years in Shandong Province.
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