Analysis of factors influencing the health-related quality of life in patients with cervical cancer based on FACT-Cx (V4.0)

Objective To evaluate the health-related quality of life (HRQOL) and its influencing factors in patients with cervical cancer. Methods 120 inpatients with cervical cancer at Yunnan Tumor Hospital were investigated by functional assessment of cancer therapy-cervix (FACT-Cx), t-test, analysis of variance and multiple linear regression were used to analyze factors influencing the HRQOL. Results The total HRQOL score of patients was (104.88±19.51), and the domain scores of physical well-being (PWB), social/family well-being (SWB), emotional well-being (EWB), functional well-being (FWB), cervical cancer subscale (CxS) were (20.41±5.46), (17.17±6.10), (15.73±5.06), (13.34±5.83), (38.23±6.26), respectively. Based on multiple linear regression,the influencing factors of PWB were marital status and clinical stages, the influencing factor of SWB was marital status, the influencing factors of EWB were education levels and clinical stages, the influencing factors of FWB, CxS and total score were all marital status, clinical stages and education levels. Conclusions The HRQOL scores were influenced by a number of factors and it is significant to improve HRQOL in patients with cervical cancer by relieving symptoms and reducing treatment side effects according to patients' specialty, also psychological support and encouragement was essential.