A prospective study on the association between body mass index and all-cause mortality in type 2 diabetic patients

LI Ying; SU Jian; YU Hao; QIN Yu; LUO Peng-fei; PAN En-chun; ZHANG Ning; SHEN Chong; ZHOU Jin-yi; WU Ming

doi:10.16462/j.cnki.zhjbkz.2019.08.012

Volume 23 Issue 8

Aug. 2019

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Article Navigation > CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION > 2019 > 23(8): 945-950

LI Ying, SU Jian, YU Hao, QIN Yu, LUO Peng-fei, PAN En-chun, ZHANG Ning, SHEN Chong, ZHOU Jin-yi, WU Ming. A prospective study on the association between body mass index and all-cause mortality in type 2 diabetic patients[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2019, 23(8): 945-950. doi: 10.16462/j.cnki.zhjbkz.2019.08.012

Citation:

LI Ying, SU Jian, YU Hao, QIN Yu, LUO Peng-fei, PAN En-chun, ZHANG Ning, SHEN Chong, ZHOU Jin-yi, WU Ming. A prospective study on the association between body mass index and all-cause mortality in type 2 diabetic patients[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2019, 23(8): 945-950. doi: 10.16462/j.cnki.zhjbkz.2019.08.012

Citation:

LI Ying, SU Jian, YU Hao, QIN Yu, LUO Peng-fei, PAN En-chun, ZHANG Ning, SHEN Chong, ZHOU Jin-yi, WU Ming. A prospective study on the association between body mass index and all-cause mortality in type 2 diabetic patients[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2019, 23(8): 945-950. doi: 10.16462/j.cnki.zhjbkz.2019.08.012

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A prospective study on the association between body mass index and all-cause mortality in type 2 diabetic patients

doi: 10.16462/j.cnki.zhjbkz.2019.08.012

LI Ying¹,
SU Jian²,
YU Hao²,
QIN Yu²,
LUO Peng-fei²,
PAN En-chun^{2, 3},
ZHANG Ning⁴,
SHEN Chong⁵,
ZHOU Jin-yi²,
WU Ming^{1, 2
,
,}

1.
School of Public Health, Southeast University, Nanjing 210009, China
2.
Department of Non-communicable Chronic Disease Control, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China
3.
Huai'an Center for Disease Control and Prevention, Huai'an 223001, China
4.
Changshu Center for Disease Control and Prevention, Changshu 215500, China
5.
Department of Epidemiology and Health Statistics, School of Public Health, Nanjing Medical University, Nanjing 210009, China

Funds:

Medical Leading Talent and Innovation Team of Jiangsu Province K201105

Jiangsu Provincial Fourth "333 Project" BRA2013107

Science and Education Strong Industry Engineering Young Talents of Jiangsu Provincial Center for Disease Control and Prevention JKRC2016007

Jiangsu Provincial Graduate Student Practice Innovation Plan SJCX18-0080

More Information

Corresponding author: WU Ming, E-mail: jswuming@vip.sina.com
Received Date: 2018-12-18
Rev Recd Date: 2019-04-02
Publish Date: 2019-08-10

Abstract

Abstract

Objective The aim is to investigate the association between body mass index (BMI) and risk of all-cause mortality among patients with type 2 diabetes. Methods A total of 17 638 patients with type 2 diabetes registered in the management of National Basic Public Health Services in two areas of southern and northern Jiangsu were recruited. Cox proportional risk regression model was used to calculate the hazard ratio(HR) value and 95% confidence interval (95% CI) of different BMI groups in the follow-up period. Results The subjects were followed up for a total of 77 451 person-years with an average duration of 4.39 years, and 1 274 patients died during the follow-up period. The number of death in low weight group (BMI < 18.5 kg/m²), normal weight group (18.5 kg/m² ≤ BMI < 24 kg/m²), overweight (24 kg/m² ≤ BMI < 28 kg/m²) and obese group (BMI ≥ 28 kg/m²) were 39, 575, 484 and 176 respectively.The corresponding mortalities were 15.6%, 9.5%, 6.2% and 5.1%, respectively. Compared to normal weight group, the adjusted HR of all-cause mortality in low weight, overweight and obese group were 1.66 (95% CI: 1.20-2.30), 0.68 (95% CI: 0.61-0.77), 0.58 (95% CI: 0.48-0.68), respectively. Conclusions Low-weight patients have the highest risk of all-cause mortality compared with normal counterparts, while both overweight and obese people have a lower risk of death. Overweight and obesity may reduce the risk of all-cause mortality in type 2 diabetic patients.
- Body mass index,
- Death risk,
- Diabetes mellitus,
- Cohort study

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References(23)

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