Association of obesity and brachial-ankle pulse wave velocity among type 2 diabetes patients

HUANG Zhe; XU Bei-bei; WANG Xiao-wen; YAO Shan-shan; CAO Gui-ying; LI Man; CAO Ya-ying; TIAN Yao-hua; WU Yao; HUANG Shao-ping; LIU Xiao-fen; QIN Xue-ying; TANG Xun; LI Jin; WU Tao; CHEN Da-fang; HU Yong-hua

doi:10.16462/j.cnki.zhjbkz.2019.09.014

Volume 23 Issue 9

Sep. 2019

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Article Navigation > CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION > 2019 > 23(9): 1086-1091

HUANG Zhe, XU Bei-bei, WANG Xiao-wen, YAO Shan-shan, CAO Gui-ying, LI Man, CAO Ya-ying, TIAN Yao-hua, WU Yao, HUANG Shao-ping, LIU Xiao-fen, QIN Xue-ying, TANG Xun, LI Jin, WU Tao, CHEN Da-fang, HU Yong-hua. Association of obesity and brachial-ankle pulse wave velocity among type 2 diabetes patients[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2019, 23(9): 1086-1091. doi: 10.16462/j.cnki.zhjbkz.2019.09.014

Citation:

HUANG Zhe, XU Bei-bei, WANG Xiao-wen, YAO Shan-shan, CAO Gui-ying, LI Man, CAO Ya-ying, TIAN Yao-hua, WU Yao, HUANG Shao-ping, LIU Xiao-fen, QIN Xue-ying, TANG Xun, LI Jin, WU Tao, CHEN Da-fang, HU Yong-hua. Association of obesity and brachial-ankle pulse wave velocity among type 2 diabetes patients[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2019, 23(9): 1086-1091. doi: 10.16462/j.cnki.zhjbkz.2019.09.014

Citation:

HUANG Zhe, XU Bei-bei, WANG Xiao-wen, YAO Shan-shan, CAO Gui-ying, LI Man, CAO Ya-ying, TIAN Yao-hua, WU Yao, HUANG Shao-ping, LIU Xiao-fen, QIN Xue-ying, TANG Xun, LI Jin, WU Tao, CHEN Da-fang, HU Yong-hua. Association of obesity and brachial-ankle pulse wave velocity among type 2 diabetes patients[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2019, 23(9): 1086-1091. doi: 10.16462/j.cnki.zhjbkz.2019.09.014

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Association of obesity and brachial-ankle pulse wave velocity among type 2 diabetes patients

doi: 10.16462/j.cnki.zhjbkz.2019.09.014

1.
Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China
2.
Peking University Medical Informatics Center, Beijing 100191, China
3.
General Office, Fangshan District Center for Disease Control and Prevention, Beijing 102401, China
4.
Department of Chronic Disease, Fangshan District Center for Disease Control and Prevention, Beijing 102488, China

Funds:

National Natural Science Foundation of China 81230066

National Natural Science Foundation of China 81473043

National Natural Science Foundation of China 81872695

More Information

Corresponding author: HU Yong-hua, E-mail: yhhu@bjmu.edu.cn
Received Date: 2019-03-26
Rev Recd Date: 2019-06-25
Publish Date: 2019-09-10

Abstract

Abstract

Objective The aim of this study was to investigate associations of overall obesity (OO) and abdominal obesity (AO) with brachial-ankle pulse wave velocity (baPWV) among type 2 diabetes(T2DM) patients. Methods A community-based study for T2DM patients was conducted in rural communities in Beijing.Every patient completed a questionnaire to collect demography, lifestyle and diseases history, and underwent physical examinations, baPWV assessments and blood biochemical tests. Multivariate linear regression was used to assess the relationship between obesity index and baPWV. Abnormal baPWV was defined as patients with baPWV ≥ 1, 700 cm/s. Logistic regression model was performed to explore the risk of abnormal baPWV after adjusting for poetential confounders step by step. Results A total of 2 048 T2DM patients were recruited. The average age was (59.2±8.3) years and total prevalence of abnormal baPWV was 49.7%. After multivariable adjustment, linear regression showed that there was a negative correlation between body mass index(BMI) and baPWV and a positive correlation between waist-to-hip ratio (WHR) and baPWV. Compared to normal weight group, those with BMI ≥ 28 kg/m² had lower risk of abnormal baPWV (OR=0.59, 95% CI: 0.44-0.78, P < 0.001), but there was an increased risk of 46% among patients with obesity in WHR (OR=1.46, 95% CI: 1.07-2.00, P=0.018). Compared to those without OO and AO, patients without OO but with AO had a 1.67-fold increasesd risk of abnormal baPWV (OR=1.67, 95% CI: 1.19-2.35, P=0.003). Conclusions Abdominal obesity is related with arterial stiffnening among T2DM patients, and it is critical to evaluate arterial stiffness of T2DM patients with abdmonal obesity and normal BMI in order to reduce future risk of cardiovascular diseases.
- Diabetes,
- Overall obesity,
- Abdominal obesity,
- Arterial stiffness

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References(20)

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