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CN 34-1304/RISSN 1674-3679

Volume 25 Issue 2
Feb.  2021
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SHI Ying-jie, ZHAN Yong-le, CHEN Yun-li, JIANG Yu, MA Liang-kun. Influencing factors of preterm birth: a prospective cohort study[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(2): 143-148. doi: 10.16462/j.cnki.zhjbkz.2021.02.005
Citation: SHI Ying-jie, ZHAN Yong-le, CHEN Yun-li, JIANG Yu, MA Liang-kun. Influencing factors of preterm birth: a prospective cohort study[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(2): 143-148. doi: 10.16462/j.cnki.zhjbkz.2021.02.005

Influencing factors of preterm birth: a prospective cohort study

doi: 10.16462/j.cnki.zhjbkz.2021.02.005
Funds:

CAMS Innovation Fund for Medical Sciences 2019-I2M-2-007

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  •   Objective  To analyze the prevalence and risk factors of preterm birth in China and to provide reference for the prevention of preterm birth.  Methods  Data was from the Chinese Pregnant Women Cohort study (CPWCS). The basic information and delivery outcomes of pregnant women were collected through questionnaire surveys and hospital information system. The chi-square test and multivariate logistic regression analysis were conducted by SPSS 26.0 software.  Results  The prevalence of preterm birth among 5 671 pregnant women was 5.2%, and there was no significant difference in the prevalence of preterm birth among different regions (χ2 =0.591, P=0.771). The results of multivariate logistic regression analysis showed that advanced age, history of diabetes, history of premature birth, placental abruption, premature rupture of membranes, fetal distress, hypertension during pregnancy, and twins were risk factors for preterm birth (all P < 0.05), while among pregnant women who give birth naturally, advanced age (OR=2.90, 95% CI: 1.67-5.06, P < 0.001), premature rupture of membranes (OR=6.17, 95% CI: 4.21-9.06, P < 0.001), and twins (OR=17.72, 95% CI: 3.23-97.25, P < 0.001) were risk factors for preterm birth.  Conclusions  There are many influencing factors of preterm birth. Accurately identifying risk factors and providing pregnant women with scientific and reasonable health education and individualized prevention and control measures are important means to prevent preterm birth.
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