Chronic ozone exposure and depression among middle-aged and elderly people in China

DU Peng; ZHANG Wen-jing; ZHANG Yi; CHEN Chen; FANG Jian-long; LI Tian-tian; SHI Xiao-ming

doi:10.16462/j.cnki.zhjbkz.2021.10.003

Volume 25 Issue 10

Nov. 2021

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Article Navigation > CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION > 2021 > 25(10): 1126-1132, 1138

DU Peng, ZHANG Wen-jing, ZHANG Yi, CHEN Chen, FANG Jian-long, LI Tian-tian, SHI Xiao-ming. Chronic ozone exposure and depression among middle-aged and elderly people in China[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(10): 1126-1132, 1138. doi: 10.16462/j.cnki.zhjbkz.2021.10.003

Citation:

DU Peng, ZHANG Wen-jing, ZHANG Yi, CHEN Chen, FANG Jian-long, LI Tian-tian, SHI Xiao-ming. Chronic ozone exposure and depression among middle-aged and elderly people in China[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(10): 1126-1132, 1138. doi: 10.16462/j.cnki.zhjbkz.2021.10.003

Citation:

DU Peng, ZHANG Wen-jing, ZHANG Yi, CHEN Chen, FANG Jian-long, LI Tian-tian, SHI Xiao-ming. Chronic ozone exposure and depression among middle-aged and elderly people in China[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(10): 1126-1132, 1138. doi: 10.16462/j.cnki.zhjbkz.2021.10.003

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Chronic ozone exposure and depression among middle-aged and elderly people in China

doi: 10.16462/j.cnki.zhjbkz.2021.10.003

DU Peng¹,
ZHANG Wen-jing^{1, 2},
ZHANG Yi¹,
CHEN Chen¹,
FANG Jian-long¹,
LI Tian-tian^{1, 2
,
,},
SHI Xiao-ming^{1, 2
,
,}

1.
China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China
2.
School of Public Health, Nanjing Medical University, Nanjing 211166, China

Funds:

National Key Research and Development Program of China 2016YFC0206500

National Research Program for Key Issues in Air Pollution Control DQGG0401

More Information

Corresponding author: LI Tian-tian, E-mail: litiantian@nieh.chinacdc.cn; SHI Xiao-ming, E-mail: shixm@chinacdc.cn
Received Date: 2021-06-09
Rev Recd Date: 2021-09-16

Available Online: 2021-11-17

Publish Date: 2021-10-10

Abstract

Abstract

Objective To investigate the association between chronic ozone (O₃) exposure and depression among middle-aged and elderly people in China, in order to provide guidance for prevention and intervention of depression. Methods Among key areas for air pollution control in China, according to strict inclusion criteria for study sites and population, 8 584 participates aged 40~ < 90 from 45 districts/counties in 16 provinces were randomly selected and recruited using a stratified random sampling method. The demographic characteristics, socioeconomic factors, disease and symptom information were obtained through face-to-face questionnaire survey, and the depression was measured by Patient Health Questionnaire 9 (PHQ-9). One- and two-year moving average concentrations of air pollutant prior to the survey were calculated, referring to the data from the closest environmental monitoring station. The multivariate Logistic regression model was constructed to analyze the association between chronic O₃ exposure and depression. Results The prevalence of depression was 6.79% (n=583) among the selected 8 584 participates. Statistically significant association between chronic O₃ exposure and depression was not found from Logistic regression analysis model. The maximum OR value was 1.04 (95% CI: 0.96-1.13, P=0.326) for each 10 μg/m³ increase of two-year moving average concentrations of O₃. In subgroup analysis, the stronger associations were observed in male and current smoking participants compared with female and never smoking individuals, and these differences were statistically significant (all P < 0.05). Moreover, modification effects of particulate matter smaller than 2.5 μm in aerodynamic diameter (PM_2.5) and annual temperature were found on the O₃-depression associations. Low PM_2.5 concentrations (≤25th percentile in all districts/counties) and high temperature (≥75th percentile in all districts/counties) conditions enhanced the effects of O₃ on depression. Conclusion Our findings indicated statistically positive association of O₃ exposure and depression among male, current smoking individuals, population in low PM_2.5 concentration and high temperature conditions.
- Ozone,
- Chronic exposure,
- Middle-aged and elderly,
- Depression,
- Association

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References(37)

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