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CN 34-1304/RISSN 1674-3679

Volume 25 Issue 10
Nov.  2021
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YANG Jia-lu, LUO Yan-fang, SHAN Ren-hu, ZUO Zhi-gang, YU Zhen, CHEN Wu-nong, ZHU Yao-wen, LI Liu-qing, LUO Shi-yun, YE Yong-xin, ZHANG Zhuo-yu, LI Rui, JU Jing-meng, ZHU Shan-shan, FAN Jia-hua, XIA Min. The prevalence of the metabolic associated fatty liver disease among residents aged 30 to 79 in Dongguan City of Guangdong Province[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(10): 1175-1179, 1230. doi: 10.16462/j.cnki.zhjbkz.2021.10.011
Citation: YANG Jia-lu, LUO Yan-fang, SHAN Ren-hu, ZUO Zhi-gang, YU Zhen, CHEN Wu-nong, ZHU Yao-wen, LI Liu-qing, LUO Shi-yun, YE Yong-xin, ZHANG Zhuo-yu, LI Rui, JU Jing-meng, ZHU Shan-shan, FAN Jia-hua, XIA Min. The prevalence of the metabolic associated fatty liver disease among residents aged 30 to 79 in Dongguan City of Guangdong Province[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(10): 1175-1179, 1230. doi: 10.16462/j.cnki.zhjbkz.2021.10.011

The prevalence of the metabolic associated fatty liver disease among residents aged 30 to 79 in Dongguan City of Guangdong Province

doi: 10.16462/j.cnki.zhjbkz.2021.10.011
Funds:

National Key Research and Development Program of China 2017YFC0907100

More Information
  • Corresponding author: XIA Min, E-mail: xiamin@mail.sysu.edu.cn
  • Received Date: 2021-06-07
  • Rev Recd Date: 2021-09-15
  • Available Online: 2021-11-17
  • Publish Date: 2021-10-10
  •   Objective  To explore the prevalence of metabolic associated fatty liver disease (MAFLD) and the impact of different characteristics among residents aged 30 to 79 in Dongguan City of Guangdong Province.  Methods  Baseline data were collected in Dongguan City, Guangdong Province of South China Cohort, including physical examination, ultrasound, and laboratory tests. According to the inclusion and exclusion criteria, we included 8 670 participants and defined the status of MAFLD referred to the consensus statement of international experts. Multivariate Logistic regression analysis model was used to analyze the factors according to gender.  Results  The prevalence of MAFLD was 31.85% among residents aged 30 to 79 in Dongguan City. The prevalence was similar among males in different age groups (χ2 =2.958, P=0.565), while it linearly increased with age in females (χtrend2=81.429, P < 0.001). The prevalence showed a linear increase with BMI, FPG, ALT, TG, TC, uric acid (UA) while a linear decrease with HDL-C. The results of multivariate Logistic regression analysis model showed that females ≥50 years old had a higher risk of MAFLD (OR=2.37, 95% CI: 1.74~3.23, P < 0.001).  Conclusions  The prevalence of MAFLD was 31.85% among residents aged 30 to 79 in Dongguan City, and there was a linear association between the prevalence of MAFLD and various metabolic indices including BMI, FPG, TG, and TC. Age ≥50 years old may be a risk factor of MAFLD in females.
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