The detection of hypercalciuria and influencing factors among people aged 18-75 years old in six provinces of China

ZHANG Bei-bei; LIU Min; LI Yuan; ZHANG Pu-hong; BAI Ya-min; JI Ning; WU Jing; XU Jian-wei

doi:10.16462/j.cnki.zhjbkz.2022.07.004

Volume 26 Issue 7

Jul. 2022

Turn off MathJax

Article Contents

Article Navigation > CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION > 2022 > 26(7): 766-770

ZHANG Bei-bei, LIU Min, LI Yuan, ZHANG Pu-hong, BAI Ya-min, JI Ning, WU Jing, XU Jian-wei. The detection of hypercalciuria and influencing factors among people aged 18-75 years old in six provinces of China[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(7): 766-770. doi: 10.16462/j.cnki.zhjbkz.2022.07.004

Citation:

ZHANG Bei-bei, LIU Min, LI Yuan, ZHANG Pu-hong, BAI Ya-min, JI Ning, WU Jing, XU Jian-wei. The detection of hypercalciuria and influencing factors among people aged 18-75 years old in six provinces of China[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(7): 766-770. doi: 10.16462/j.cnki.zhjbkz.2022.07.004

Citation:

ZHANG Bei-bei, LIU Min, LI Yuan, ZHANG Pu-hong, BAI Ya-min, JI Ning, WU Jing, XU Jian-wei. The detection of hypercalciuria and influencing factors among people aged 18-75 years old in six provinces of China[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(7): 766-770. doi: 10.16462/j.cnki.zhjbkz.2022.07.004

PDF( 817 KB)

The detection of hypercalciuria and influencing factors among people aged 18-75 years old in six provinces of China

doi: 10.16462/j.cnki.zhjbkz.2022.07.004

1.
Chronic Disease Department of Xiangyang Center for Disease Control and Prevention, Xiangyang 441000, China
2.
National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China
3.
The George Institute for Global Health at Peking University Health Science Center, Beijing 100088, China

Funds:

National Institute for Health Research Global Health Research Unit Action on Salt China 16/136/77

More Information

Corresponding author: XU Jian-wei, E-mail: xujianwei@ncncd.chinacdc.cn
Received Date: 2021-10-27
Rev Recd Date: 2022-03-23

Available Online: 2022-07-19

Publish Date: 2022-07-10

Abstract

Abstract

Objective To investigate the detection of hypercalciuria and influencing factors among people aged 18-75 years old in six Provinces of China, and to provide basis for prevention of hypercalciuria and other diseases. Methods A total of 2 693 subjects aged 18-75 years old were selected from 6 provinces in China. Using multi-stage cluster random sampling method. Information were collected through questionnaire survey, physical measurement and 24-hours urine collection (24HUC). The 24-hours urinary calcium level was measured. Results A total of 2 637 subjects were included in the final analysis, of which 258 subjects were detected with hypercalciuria, and the detection rate was 9.78%. The male and female hypercalciuria detection rates were 8.47% and 11.09%, respectively (χ² =5.124, P=0.024). Multivariate Logistic regression analysis showed that female (OR=1.366, 95% CI: 1.051-1.778, P=0.020), people aged 45- < 60 years old (OR=2.069, 95% CI: 1.404-3.049, P < 0.001), overweight (OR=1.661, 95% CI: 1.216-2.268, P=0.001), obesity (OR=2.623, 95% CI: 1.855-3.709, P < 0.001), and people with diabetes mellitus (OR=1.988, 95% CI: 1.292-3.060, P=0.002) were related with hypercalciuria. Conclusions The detection rate of hypercalciuria in Chinese population is high. It is suggested that 24HUC screening should be carried out in target population to prevent hypercalciuria and other diseases as soon as possible.
- Hypercalciuria,
- 24-hours urinary calcium,
- Influencing factors

FullText(HTML)

References(28)

References

[1]	Taylor JG, Bushinsky DA. Calcium and phosphorus homeostasis[J]. Blood Purif, 2009, 27(4): 387-394. DOI: 10.1159/000209740.
[2]	Park S, Pearle MS. Pathophysiology and management of calcium stones[J]. Urol Clin North Am, 2007, 34(3): 323-334. DOI: 10.1016/j.ucl.2007.04.009.
[3]	Liern M, Bohorquez M, Vallejo G. Treatment of idiopathic hypercalciuria and its impact on associated diseases[J]. Arch Argent Pediatr, 2013, 111(2): 110-114. DOI: 10.1590/S0325-00752013000200005.
[4]	María SG, María DCC, Antonio P, et al. The value of hypercalciuria in patients with osteopenia versus osteoporosis[J]. Urolithiasis, 2017, 45(3): 279-283. DOI: 10.1007/s00240-016-0909-2.
[5]	Martínez GM, Trincado AP, Pérez FL, et al. A comparison of induced effects on urinary calcium by thiazides and different dietary salt doses: implications in clinical practice[J]. Nefrologia (Engl Ed), 2019, 39(1): 73-79. DOI: 10.1016/j.nefro.2018.05.008.
[6]	Gul A, Ozer S, Yilmaz R, et al. Prevalence of hypercalciuria and urinary calcium excretion in school-aged children in the province of Tokat[J]. Turk Pediatri Ars, 2016, 51(4): 193-197. DOI: 10.5152/TurkPediatriArs.2016.4162.
[7]	刘高丽, 谷存国, 王洁. 漯河市儿童尿钙含量的分析研究[J]. 中国卫生检验杂志, 2016, 26(12): 1786-1787. https://www.cnki.com.cn/Article/CJFDTOTAL-ZWJZ201612040.htm Liu GL, Gu CG, Wang J. Analysis of urinary calcium contentin children of Luohe[J]. Chin J Health Lab Tee, 2016, 26(12): 1786-1787. https://www.cnki.com.cn/Article/CJFDTOTAL-ZWJZ201612040.htm
[8]	中国高血压防治指南修订委员会. 中国高血压防治指南2010[J]. 中华心血管病杂志, 2011, 39(7): 579-616. DOI: 10.3760/cmaj.issn.0253-3758.2011.07.002. Writing Group of 2010 Chinese Guidelines for the Management of Hypertension. 2010 Chinese guidelines for the management of hypertention[J]. Chin J Cardiol, 2011, 39(7): 579-616. DOI: 10.3760/cma.j.issn.0253-3758.2011.07.002.
[9]	中华医学会糖尿病学分会. 中国2型糖尿病防治指南(2020年版)[J]. 中华糖尿病杂志, 2021, 13(4): 315-409. DOI: 10.3760/cma.j.cn311282-20210304-00142. Chinese Diabetes Society. Guidelines for the prevention and control of type 2 diabets in China (2020 Edition)[J]. Chin J Pract Intern Med, 2021, 13(4): 315-409. DOI: 10.3760/cma.j.cn311282-20210304-00142.
[10]	Chen CM, Lu FC. The guidelines for prevention and control of overweight and obesity in Chinese adults[J]. Biomed Environ Sci, 2004, 17 Suppl: 1-36.
[11]	Worcester EM, Coe FL. New insights into the pathogenesis of idiopathic hypercalciuria[J]. Semin Nephrol, 2008, 28(2): 120-132. DOI: 10.1016/j.semnephrol.2008.01.005.
[12]	Li Y, Zhang P, Wu J, et al. Twenty-four-hour urinary sodium and potassium excretin and their associations with blood pressure among adults in China: baseline survey of action on salt China[J]. Hypertension, 2020, 76(5): 1580-1588. DOI: 10.1161/HYPERTENSIONAHA.120.15238.
[13]	柴琳, 张俊. 老年女性骨质疏松患者骨转换生化标志物的分析[J]. 检验医学与临床, 2008, 8(8): 986-987. DOI: 10.3969/j.issn.1672-9455.2011.08.049. Chai L, Zhang J. Analysis of biochemical markers of bone turnover in elderly women with osteoporosis[J]. Lab Med Clin, 2008, 8(8): 986-987. DOI: 10.3969/j.issn.1672-9455.2011.08.049.
[14]	Sönmez F, Akçanal B, Altincik A, et al. Urinary calcium excretion in healthy Turkish children[J]. Int Urol Nephrol, 2007, 39(3): 917-922. DOI: 10.1007/s11255-006-9013-9.
[15]	Dacia CG, Pilar P, Ana M, et al. Search for hidden secondary causes in postmenopau-sal women with osteoporosis[J]. Menopause, 2010, 17(1): 135-139. DOI: 10.1097/gme.0b013e3181ade8e5.
[16]	Leslie SW, Sajjad H. Hypercalciuria[M]. Treasure Island: StatPearls Publishing, 2021.
[17]	Leslie SW, Sajjad H, Bashir K. 24-hour urine testing for nephrolithiasis interpretation[M]. Treasure Island: StatPearls Publishing, 2022.
[18]	David SG, Joan HP, Fredric LC. Renal stone disease in older adults[J]. Clin Geriatr Med, 1998, 14(2): 367-381. doi: 10.1016/S0749-0690(18)30122-8
[19]	Curhan GC, Willett WC, Speizer FE, et al. Twenty-four-hour urine chemistries and the risk of kidney stones among women and men[J]. Kidney Int, 2001, 59(6): 2290-2298. DOI: 10.1046/j.1523-1755.2001.00746.x.
[20]	Patrícia CD, Carmen RA, Natália BC, et al. The role of salt abuse on risk for hypercalciuria[J]. Nutr J, 2011, 10: 3. DOI: 10.1186/1475-2891-10-3.
[21]	Majuran P, Erin BW, Jennifer AS, et al. Effect of demographics on excretion of key urinary factors related to kidney stone risk[J]. Urology, 2015, 86(4): 690-696. DOI: 10.1016/j.urology.2015.07.012.
[22]	Friedlander JI, Moreira DM, Hartman C, et al. Age-related changes in 24-hour urine composition must be considered in the medical management of nephrolithiasis[J]. J Endourol, 2014, 28(7): 871-876. DOI: 10.1089/end.2014.0002.
[23]	Otto BJ, Bozorgmehri S, Kuo J, et al. Age, body mass index, and gender predict 24-hour urine parameters in recurrent idiopathic calcium oxalate stone formers[J]. J Endourol, 2017, 31(12): 1335-1341. DOI: 10.1089/end.2017.0352.
[24]	Wang Q, Hu WJ, Lu YC, et al. The impact of body mass index on quantitative 24-h urine chemistries in stone forming patients: a systematic review and meta-analysis[J]. Urolithiasis, 2018, 46(6): 523-533. DOI: 10.1007/s00240-018-1044-z.
[25]	Shavit L, Ferraro PM, Johri N, et al. Effect of being overweight on urinary metabolic risk factors for kidney stone formation[J]. Nephrol Dial Transplant, 2015, 30(4): 607-613. DOI: 10.1093/ndt/gfu350.
[26]	Liu Y, Zhou L, Liu Z, et al. Higher blood urea nitrogen and urinary calcium: new risk factors for diabetes mellitus in primary aldosteronism patients[J]. Front Endocrinol (Lausanne), 2020, 11: 23. DOI: 10.3389/fendo.2020.00023.
[27]	Zhu W, Mai Z, Qin J, et al. Difference in 24-hour urine composition between diabetic and non-diabetic adults without nephrolithiasis[J]. PLoS One, 2016, 11(2): e150006. DOI: 10.1371/journal.pone.0150006.
[28]	Laube N, Pullmann M, Hergarten S, et al. Influence of urinary stones on the composition of a 24-hour urine sample[J]. Clin Chem, 2003, 49(2): 281-285. DOI: 10.1373/49.2.281.