Interaction effects between tobacco exposure and overweight on abnormal blood pressure in coking workers

WANG Yong; ZHAO Xin-yu; LIU Lu; FENG Quan; WEI Jia-jun; GUO Lan; YANG Jin

doi:10.16462/j.cnki.zhjbkz.2022.08.009

Volume 26 Issue 8

Aug. 2022

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WANG Yong, ZHAO Xin-yu, LIU Lu, FENG Quan, WEI Jia-jun, GUO Lan, YANG Jin. Interaction effects between tobacco exposure and overweight on abnormal blood pressure in coking workers[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(8): 922-926. doi: 10.16462/j.cnki.zhjbkz.2022.08.009

Citation:

WANG Yong, ZHAO Xin-yu, LIU Lu, FENG Quan, WEI Jia-jun, GUO Lan, YANG Jin. Interaction effects between tobacco exposure and overweight on abnormal blood pressure in coking workers[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(8): 922-926. doi: 10.16462/j.cnki.zhjbkz.2022.08.009

Citation:

WANG Yong, ZHAO Xin-yu, LIU Lu, FENG Quan, WEI Jia-jun, GUO Lan, YANG Jin. Interaction effects between tobacco exposure and overweight on abnormal blood pressure in coking workers[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(8): 922-926. doi: 10.16462/j.cnki.zhjbkz.2022.08.009

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Interaction effects between tobacco exposure and overweight on abnormal blood pressure in coking workers

doi: 10.16462/j.cnki.zhjbkz.2022.08.009

Department of Occupational Health, School of Public Health, Shanxi Medical University, NHC Key Laboratory of Pneumoconiosis in ShanXi, Taiyuan 030001, China

Funds:

National Natural Science Foundation of China 81273041

Natural Science Foundation of Shanxi Province of China 202103021224230

Shanxi Province Overseas Study Fund Project HGKY2019053

More Information

Corresponding author: YANG Jin, E-mail: yang_jin@sxmu.edu.cn
Received Date: 2022-03-24
Rev Recd Date: 2022-06-14

Available Online: 2022-08-23

Publish Date: 2022-08-10

Abstract

Abstract

Objective To analyze the interaction effects between tobacco exposure and overweight on abnormal blood pressure in coke-oven workers. Methods In this cross-sectional study, we collected basic information and urine sample of 700 workers in a coking plant in Shanxi Province in 2017. Polycyclic aromatic hydrocarbons (PAHs) and tobacco metabolites in the urine of workers were detected by high performance liquid chromatography-mass spectrometry. Least absolute shrinkage and selection operator regression was used to screen out the optimal risk factors associated with hypertension. Modified poisson regression was used to analyze the association between tobacco exposure and abnormal blood pressure. The interaction effects of tobacco metabolites and overweight on abnormal blood pressure in coke-oven workers was studied by interaction effects analysis. Results The logarithmic value of urine tobacco metabolites were divided into 3 groups according to the tertile (T1, T2 and T3). The modified poisson regression model showed that for each unit increase in urinary nicotine concentration in T3 (≥36.76 ng/mL), compared with T1 (< 1.54 ng/mL), the risk of abnormal blood pressure increased 1.46 (PR=2.46, 95% CI: 1.17-5.18, P=0.036). The median body mass index (BMI) of workers with abnormal blood pressure (25.85 kg/m²) was higher than that of those with normal blood pressure(24.19 kg/m²). Interaction effects analysis showed that overweight people with high nicotine levels had a significantly higher risk of hypertension than non-overweight people with low urinary nicotine levels (PR=5.12, 95% CI: 1.76-14.92, P=0.042). Conclusions BMI and urine-nicotine levels have an interactive effect on abnormal blood pressure in coke-oven workers. Controlling smoking and body weight is important to prevent hypertension in coke oven workers.
- BMI,
- Hypertension,
- Tobacco metabolites,
- Least absolute shrinkage and selection operator regression

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References(14)

References

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