Epidemiological investigation of a family clustering of COVID-19 caused by SARS-CoV-2 Delta variant in Guangzhou, China

HE Shi-yu; MIAO Yu-tian; HAN Zhi-gang; LUO Ye-fei; CAI Yan-shan; MA Meng-meng; CHEN Yuan-yuan; CHEN Zong-qiu; YUAN Jun; GU Yu-zhou

doi:10.16462/j.cnki.zhjbkz.2023.03.016

Volume 27 Issue 3

Mar. 2023

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Article Navigation > CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION > 2023 > 27(3): 334-338

HE Shi-yu, MIAO Yu-tian, HAN Zhi-gang, LUO Ye-fei, CAI Yan-shan, MA Meng-meng, CHEN Yuan-yuan, CHEN Zong-qiu, YUAN Jun, GU Yu-zhou. Epidemiological investigation of a family clustering of COVID-19 caused by SARS-CoV-2 Delta variant in Guangzhou, China[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2023, 27(3): 334-338. doi: 10.16462/j.cnki.zhjbkz.2023.03.016

Citation:

HE Shi-yu, MIAO Yu-tian, HAN Zhi-gang, LUO Ye-fei, CAI Yan-shan, MA Meng-meng, CHEN Yuan-yuan, CHEN Zong-qiu, YUAN Jun, GU Yu-zhou. Epidemiological investigation of a family clustering of COVID-19 caused by SARS-CoV-2 Delta variant in Guangzhou, China[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2023, 27(3): 334-338. doi: 10.16462/j.cnki.zhjbkz.2023.03.016

Citation:

HE Shi-yu, MIAO Yu-tian, HAN Zhi-gang, LUO Ye-fei, CAI Yan-shan, MA Meng-meng, CHEN Yuan-yuan, CHEN Zong-qiu, YUAN Jun, GU Yu-zhou. Epidemiological investigation of a family clustering of COVID-19 caused by SARS-CoV-2 Delta variant in Guangzhou, China[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2023, 27(3): 334-338. doi: 10.16462/j.cnki.zhjbkz.2023.03.016

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Epidemiological investigation of a family clustering of COVID-19 caused by SARS-CoV-2 Delta variant in Guangzhou, China

doi: 10.16462/j.cnki.zhjbkz.2023.03.016

HE Shi-yu^{1, 7},
MIAO Yu-tian^{2, 7},
HAN Zhi-gang^{3, 7},
LUO Ye-fei^{3, 7},
CAI Yan-shan^{3, 7},
MA Meng-meng^{4, 7},
CHEN Yuan-yuan^{5, 7},
CHEN Zong-qiu^{1, 7},
YUAN Jun^{6, 7},
GU Yu-zhou^{3, 7
,
,}

1.
Department of Disinfection and Vector Control, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China
2.
Department of Environmental Health, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China
3.
Department of AIDS Control and Prevention, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China
4.
Department of Communicable Disease Control and Prevention, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China
5.
Department of Chronic Non-communicable Disease Control and Prevention, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China
6.
Department of Center Director, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China
7.
Institute of Public Health, Guangzhou Medical University & Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China

HE Shi-yu and MIAO Yu-tian contributed equally to this article

Funds:

The Key Project of Medicine Discipline of Guangzhou 2021-2023-11

The Key Project of Medicine Discipline of Guangzhou 2021-2023-12

Basic Research Project of Key Laboratory of Guangzhou 2021BRP004

More Information

Corresponding author: GU Yu-zhou, E-mail: yuchoukoo@foxmail.com
Received Date: 2021-10-08
Rev Recd Date: 2022-01-25

Available Online: 2023-04-04

Publish Date: 2023-03-10

Abstract

Abstract

Objective To investigate the epidemiological characteristics of a family clustering of COVID-19 caused by SARS-CoV-2 Delta (B.1.617.2) variant in Guangzhou, China. Methods The information of this case were extracted from Chinese CDC Infectious Disease Information System and epidemiological investigation. Demographic and epidemiological characteristics of this case were analyzed and described through descriptive epidemiological analysis. Results This family clustering included 6 cases, 3 of them were male, and the median age was 24.50 years. None of them accepted vaccination. 4 cases (case 1-4) of them developed symptoms successively 4-7 d after they had an exposure history in a restaurant with a confirmed case. Due to close contact, the other two family members (case 5, 6) developed symptoms 2-5 d after the onset of the 4 cases aforementioned. Case 1 and 2 were found after taking the centralized nucleic acid testing of SARS-CoV-2 in the community, case 3-6 were reported during the centralized health observation as the close contacts of case 1 and 2. A total of 24 key locations were involved in the activity trajectories of the 6 cases, and 427 close contacts were found. Except for other 4 cases, none of the close contacts were infected. Conclusions With vaccination and non-pharmaceutical interventions, focusing on stopping transmitting in family is still an important and useful strategy in preventing and controlling the community transmission of COVID-19 epidemic.
- COVID-19,
- SARS-CoV-2 Delta variant,
- Family clustering,
- Epidemiological investigation

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References(15)

References

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