Interaction between polycyclic aromatic hydrocarbons exposure and alcohol consumption: effects on mental health status in non-smokers

TAN Lina; LIU Shaohui; JING Jiajun; HU Qiuhua; PENG Yang; ZHANG Li'e; MA Xiaoli; HHUANG Haifeng; ZOU Yunfeng; WANG Mingjun

doi:10.16462/j.cnki.zhjbkz.2023.05.007

Volume 27 Issue 5

May 2023

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Article Navigation > CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION > 2023 > 27(5): 534-539

TAN Lina, LIU Shaohui, JING Jiajun, HU Qiuhua, PENG Yang, ZHANG Li'e, MA Xiaoli, HHUANG Haifeng, ZOU Yunfeng, WANG Mingjun. Interaction between polycyclic aromatic hydrocarbons exposure and alcohol consumption: effects on mental health status in non-smokers[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2023, 27(5): 534-539. doi: 10.16462/j.cnki.zhjbkz.2023.05.007

Citation:

TAN Lina, LIU Shaohui, JING Jiajun, HU Qiuhua, PENG Yang, ZHANG Li'e, MA Xiaoli, HHUANG Haifeng, ZOU Yunfeng, WANG Mingjun. Interaction between polycyclic aromatic hydrocarbons exposure and alcohol consumption: effects on mental health status in non-smokers[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2023, 27(5): 534-539. doi: 10.16462/j.cnki.zhjbkz.2023.05.007

Citation:

TAN Lina, LIU Shaohui, JING Jiajun, HU Qiuhua, PENG Yang, ZHANG Li'e, MA Xiaoli, HHUANG Haifeng, ZOU Yunfeng, WANG Mingjun. Interaction between polycyclic aromatic hydrocarbons exposure and alcohol consumption: effects on mental health status in non-smokers[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2023, 27(5): 534-539. doi: 10.16462/j.cnki.zhjbkz.2023.05.007

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Interaction between polycyclic aromatic hydrocarbons exposure and alcohol consumption: effects on mental health status in non-smokers

doi: 10.16462/j.cnki.zhjbkz.2023.05.007

TAN Lina^{1, 3},
LIU Shaohui^{2, 3},
JING Jiajun^{2, 3},
HU Qiuhua^{1, 3},
PENG Yang^{2, 3},
ZHANG Li'e^{2, 3},
MA Xiaoli^{2, 3},
HHUANG Haifeng^{1, 2},
ZOU Yunfeng^{2, 3},
WANG Mingjun^{3, 4
,
,}

1.
The First Clinical Medical College of Guangxi Medical University, Nanning 530021, China
2.
Guangxi Colleges and Universities Key Laboratory of Prevention and Control of Highly Prevalent Diseases, Guangxi Medical University, Guangxi Key Laboratory of Environment and Health Research, Guangxi Medical University, Nanning 530021, China
3.
Department of Health Toxicology and Department of Environmental Health, School of Public Health, Guangxi Medical University, Nanning 530021, China
4.
Department of Nephrology, First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China

Funds:

Guangxi Natural Science Foundation 2019GXNSFGA245002

More Information

Corresponding author: WANG Mingjun, E-mail: wmjwyy2002@163.com
Received Date: 2022-09-25
Rev Recd Date: 2023-01-15
Publish Date: 2023-05-10

Abstract

Abstract

Objective To explore the effects of polycyclic aromatic hydrocarbons (PAHs) exposure and its interaction with alcohol consumption on the mental health of non-smokers. Methods A questionnaire survey and mental health assessment were conducted among 513 non-active smokers in a large enterprise in Guangxi. The general mental health questionnaire was used to evaluate the mental health status of the subjects. Urinary hydroxypolycyclic aromatic hydrocarbons (OH-PAHs) levels were employed as an indicator of internal exposure to PAHs. Logistic regression model and generalized linear model were employed to analyze effects of PAHs exposure and its interaction with alcohol consumption on mental health status. Results The average age of the subjects in this study was (39.60±6.60) years old. 44.2% of the subjects were drinkers, with most being unmarried, male, and exposed to secondhand smoke (P < 0.05). Logistic regression analysis showed that the increase of urine concentration of 1-hydroxynaphthalene (1-OHNAP) and total hydroxynaphthalene (∑OHNAPs) was associated with the risk of poor mental health (OR=1.23, 95% CI: 1.01-1.49; OR=1.10, 95% CI: 1.00-1.21; all P < 0.05). Interaction analysis showed that compared with non-drinking and low level OH-PAHs group, the concentration of 1-OHNAP, 2-hydroxynaphthalene (2-OHNAP), ∑OHNAPs and total hydroxypolycyclic aromatic hydrocarbons (∑OHPAHs) in urine and alcohol consumption increased the risk of poor meatal health in middle-aged and older adults (OR=3.91, 95% CI: 1.01-15.11; OR=3.69, 95% CI: 1.05-12.98; OR=1.96, 95% CI: 1.01-3.80; OR=1.73, 95% CI: 1.06-2.93; all P_int < 0.05). Conclusions PAHs exposure is a risk factor for poor mental health in non-smoking populations, and alcohol consumption can exacerbate the risk of poor mental health in middle-aged and elderly non-smokers exposed to PAHs.
- Polycyclic aromatic hydrocarbons,
- Alcohol consumption,
- Mental health,
- 12-item General Health Questionnaire,
- Interactions,
- Non-smoking population

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References(21)

References

[1]	Auerbach RP, Mortier P, Bruffaerts R, et al. Mental disorder comorbidity and suicidal thoughts and behaviors in the World Health Organization World Mental Health Surveys International College student initiative [J]. Int J Methods Psychiatr Res, 2019, 28(2): e1752. DOI: 10.1002/mpr.1752.
[2]	Jacob L, Smith L, Armstrong NC, et al. Alcohol use and mental health during COVID-19 lockdown: a cross-sectional study in a sample of UK adults [J]. Drug Alcohol Depend, 2021, 219: 108488. DOI: 10.1016/j.drugalcdep.2020.108488.
[3]	Hefner KR, Sollazzo A, Mullaney S, et al. E-cigarettes, alcohol use, and mental health: use and perceptions of e-cigarettes among college students, by alcohol use and mental health status [J]. Addict Behav, 2019, 91: 12-20. DOI: 10.1016/j.addbeh.2018.10.040.
[4]	吴念韦, 杨帆, 夏静, 等. 我国中老年人抑郁现况及其影响因素分析[J]. 四川大学学报(医学版), 2021, 52(5): 767-771. DOI: 10.12182/20210960507. Wu NW, Yang F, Xia J, et al. Analysis of the status of depression and the influencing factors in middle-aged and older adults in China [J]. J Sichuan Univ (Med Sci), 2021, 52(5): 767-771. DOI: 10.12182/20210960507.
[5]	Abed Al Ahad M, Demmȟsarar U, Sullivan F, et al. Air pollution and individuals' mental well-being in the adult population in United Kingdom: a spatial-temporal longitudinal study and the moderating effect of ethnicity [J]. PLoS One, 2022, 17(3): e0264394. DOI: 10.1371/journal.pone.0264394.
[6]	Jing JJ, Zhang LE, Lu WM, et al. Household cooking oil type and risk of oral micronucleus frequency in Chinese nonsmokers [J]. Environ Pollut, 2022, 307: 119520. DOI: 10.1016/j.envpol.2022.119520.
[7]	Kim KH, Jahan SA, Kabir E, et al. A review of airborne polycyclic aromatic hydrocarbons (PAHs) and their human health effects [J]. Environ Int, 2013, 60: 71-80. DOI: 10.1016/j.envint.2013.07.019.
[8]	Rahman HH, Niemann D, Munson-McGee SH. Association among urinary polycyclic aromatic hydrocarbons and depression: a cross-sectional study from NHANES 2015-2016 [J]. Environ Sci Pollut Res, 2022, 29(9): 13089-13097. DOI: 10.1007/s11356-021-16692-3.
[9]	王馨, 张红梅, 宋展飞, 等. 血浆脑源性神经营养因子水平在多环芳烃职业暴露与焦炉工人认知功能障碍关联中的中介效应[J]. 环境与职业医学, 2022, 39(3): 315-322. DOI: 10.11836/JEOM21370. Wang X, Zhang HM, Song ZF, et al. Mediating effect of serum BDNF level on association of occupational PAHs exposure with cognitive impairment in coke oven workers [J]. Journal of Environmental and Occupational Medicine, 2022, 39(3): 315-322. DOI: 10.11836/JEOM21370.
[10]	Lees B, Meredith LR, Kirkland AE, et al. Effect of alcohol use on the adolescent brain and behavior [J]. Pharmacol Biochem Behav, 2020, 192: 172906. DOI: 10.1016/j.pbb.2020.172906.
[11]	Saura-Moreno C, Cortés-Arcas MV, Fernández-Meseguer A, et al. Root caries analysis in working population of 35-44 years of age (Spain) [J]. Med Oral Patol Oral Cir Bucal, 2017, 22(5): e527-e535. DOI: 10.4317/medoral.21685.
[12]	Goldberg DP, Gater R, Sartorius N, et al. The validity of two versions of the GHQ in the WHO study of mental illness in general health care [J]. Psychol Med, 1997, 27(1): 191-197. DOI: 10.1017/s0033291796004242.
[13]	Montaldo L, Montaldo P, Caredda E, et al. Association between exposure to secondhand smoke and sleep bruxism in children: a randomised control study [J]. Tob Control, 2012, 21(4): 392-395. DOI: 10.1136/tobaccocontrol-2011-050217.
[14]	Chang AB, Wilson SJ, Masters IB, et al. Altered arousal response in infants exposed to cigarette smoke [J]. Arch Dis Child, 2003, 88(1): 30-33. DOI: 10.1136/adc.88.1.30.
[15]	Lin CS, Huang RJ, Duan J, et al. Polycyclic aromatic hydrocarbons from cooking emissions [J]. Sci Total Environ, 2022, 818: 151700. DOI: 10.1016/j.scitotenv.2021.151700.
[16]	Spiacci A, Vilela-Costa HH, Sant'Ana AB, et al. Panic-like escape response elicited in mice by exposure to CO₂, but not hypoxia [J]. Prog Neuro Psychopharmacol Biol Psychiatry, 2018, 81: 178-186. DOI: 10.1016/j.pnpbp.2017.10.018.
[17]	Thiankhaw K, Chattipakorn N, Chattipakorn SC. PM_2.5 exposure in association with AD-related neuropathology and cognitive outcomes [J]. Environ Pollut, 2022, 292: 118320. DOI: 10.1016/j.envpol.2021.118320.
[18]	Ji XY, Liu R, Guo JJ, et al. Olfactory bulb microglia activation mediated neuronal death in real-ambient particulate matter exposure mice with depression-like behaviors [J]. Sci Total Environ, 2022, 821: 153456. DOI: 10.1016/j.scitotenv.2022.153456.
[19]	Bors L, Tóth K, Tóth EZ, et al. Age-dependent changes at the blood-brain barrier. A comparative structural and functional study in young adult and middle aged rats [J]. Brain Res Bull, 2018, 139: 269-277. DOI: 10.1016/j.brainresbull.2018.03.001.
[20]	Goncharova ND. The HPA axis under stress and aging: individual vulnerability is associated with behavioral patterns and exposure time [J]. Bioessays, 2020, 42(9): e2000007. DOI: 10.1002/bies.202000007.
[21]	Burgess DJ, Moritz KM. Prenatal alcohol exposure and developmental programming of mental illness [J]. J Dev Orig Health Dis, 2020, 11(3): 211-221. DOI: 10.1017/S2040174420000082.