Association between sex hormone levels and metabolic syndrome in a population of elderly men in Shanghai community

CHEN Yijun; WU Qiang; TANG Shuning; LIN Fangting; CHEN Xiuqin; GAO Junling; HUANG Limei; XIAO Qianyi

doi:10.16462/j.cnki.zhjbkz.2024.10.019

Volume 28 Issue 10

Oct. 2024

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CHEN Yijun, WU Qiang, TANG Shuning, LIN Fangting, CHEN Xiuqin, GAO Junling, HUANG Limei, XIAO Qianyi. Association between sex hormone levels and metabolic syndrome in a population of elderly men in Shanghai community[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2024, 28(10): 1235-1240. doi: 10.16462/j.cnki.zhjbkz.2024.10.019

Citation:

CHEN Yijun, WU Qiang, TANG Shuning, LIN Fangting, CHEN Xiuqin, GAO Junling, HUANG Limei, XIAO Qianyi. Association between sex hormone levels and metabolic syndrome in a population of elderly men in Shanghai community[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2024, 28(10): 1235-1240. doi: 10.16462/j.cnki.zhjbkz.2024.10.019

Citation:

CHEN Yijun, WU Qiang, TANG Shuning, LIN Fangting, CHEN Xiuqin, GAO Junling, HUANG Limei, XIAO Qianyi. Association between sex hormone levels and metabolic syndrome in a population of elderly men in Shanghai community[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2024, 28(10): 1235-1240. doi: 10.16462/j.cnki.zhjbkz.2024.10.019

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Association between sex hormone levels and metabolic syndrome in a population of elderly men in Shanghai community

doi: 10.16462/j.cnki.zhjbkz.2024.10.019

1.
Department of Preventive Medicine and Health Education, School of Public Health, Fudan University, Shanghai 200032, China
2.
Office of Community Health Service Center, Xinqiao Town, Songjiang District, Shanghai, Shanghai 201612, China
3.
Injury Statistics Department of Shanghai Songjiang District Center for Disease Control and Prevention, Shanghai 201600, China

Funds:

National Natural Science Foundation of China 82173592

More Information

Corresponding author: HUANG Limei, E-mail: hlm950526@163.com; XIAO Qianyi, E-mail: xiaoqianyi@fudan.edu.cn
Received Date: 2023-10-07
Rev Recd Date: 2024-03-21

Available Online: 2024-12-11

Publish Date: 2024-10-10

Abstract

Abstract

Objective To investigate the association between testosterone and estradiol levels and the components of metabolic syndrome (MetS) in elderly men aged ≥ 60 years in Shanghai communities. Methods This study included a total of 201 elderly men aged ≥ 60 from Shanghai communities. Information on age, lifestyle (including smoking, drinking, and physical activity), and medical history was gathered via a questionnaire survey. Physical measurements included height, weight, waist circumference, blood pressure (BP), fasting plasma glucose (FPG), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), and testosterone. A multivariate logistic regression model was employed to analyze the association between sex hormone levels and MetS and its components. Results After adjusting for age, smoking, drinking, physical activity, and BMI, high testosterone levels were associated with a lower risk of MetS (OR=0.76, 95% CI: 0.61-0.95, P=0.016). The results showed that compared with the lowest level group, the risk of MetS in the highest level group was reduced by 66% (T3∶T1: OR=0.34, 95% CI: 0.13-0.90, P=0.030); Compared with the lowest level group, the risk of MetS in the highest level group was reduced by 68% (T3∶T1: OR=0.32, 95% CI: 0.11-0.88, P=0.027). The analysis of MetS components showed that among older men ≥ 60 years old, the high-level testosterone group had a low risk of hyperglycemia. Conclusions The serum testosterone and estradiol levels of elderly men in Shanghai community were negatively correlated with MetS risk, and testosterone was negatively correlated with the risk of hyperglycemia in MetS components.
- Elderly men,
- Sex hormones,
- Metabolic syndrome,
- Metabolic syndrome components

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References(19)

References

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