Serological testing results of hepatitis B virus among the population of childbearing age in Jiangsu Province from 2010 to 2020

LI Menglan; WU Yulin; HUANG Lili; FENG Jie; ZHANG Ruijin; LIU Shuaimei; ZHOU Qing; LIN Ning

doi:10.16462/j.cnki.zhjbkz.2024.11.006

Volume 28 Issue 11

Nov. 2024

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LI Menglan, WU Yulin, HUANG Lili, FENG Jie, ZHANG Ruijin, LIU Shuaimei, ZHOU Qing, LIN Ning. Serological testing results of hepatitis B virus among the population of childbearing age in Jiangsu Province from 2010 to 2020[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2024, 28(11): 1275-1280. doi: 10.16462/j.cnki.zhjbkz.2024.11.006

Citation:

LI Menglan, WU Yulin, HUANG Lili, FENG Jie, ZHANG Ruijin, LIU Shuaimei, ZHOU Qing, LIN Ning. Serological testing results of hepatitis B virus among the population of childbearing age in Jiangsu Province from 2010 to 2020[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2024, 28(11): 1275-1280. doi: 10.16462/j.cnki.zhjbkz.2024.11.006

Citation:

LI Menglan, WU Yulin, HUANG Lili, FENG Jie, ZHANG Ruijin, LIU Shuaimei, ZHOU Qing, LIN Ning. Serological testing results of hepatitis B virus among the population of childbearing age in Jiangsu Province from 2010 to 2020[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2024, 28(11): 1275-1280. doi: 10.16462/j.cnki.zhjbkz.2024.11.006

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Serological testing results of hepatitis B virus among the population of childbearing age in Jiangsu Province from 2010 to 2020

doi: 10.16462/j.cnki.zhjbkz.2024.11.006

LI Menglan^{1, 2, 3},
WU Yulin^{1, 2, 3},
HUANG Lili^{1, 2, 3},
FENG Jie^{1, 2, 3},
ZHANG Ruijin^{1, 2, 3},
LIU Shuaimei^{1, 2, 3},
ZHOU Qing^{1, 2, 3},
LIN Ning^{1, 2, 3
,
,}

1.
Jiangsu Health Development Research Center, Nanjing 210036, China
2.
NHC Key Laboratory of Contraceptives Vigilance and Fertility Surveillance, Nanjing 210036, China
3.
Jiangsu Provincial Medical Key Laboratory of Fertility Protection and Health Technology Assessment, Nanjing 210036, China

Funds:

Scientific Research Project of Jiangsu Provincial Health Commission M2020101

Jiangsu Province Capability Improvement Project Through Science, Technology and Education ZDXYS202210

More Information

Corresponding author: LIN Ning, E-mail: 945230710@qq.com
Received Date: 2024-05-29
Rev Recd Date: 2024-09-03

Available Online: 2024-12-23

Publish Date: 2024-11-10

Abstract

Abstract

Objective To investigate the serological testing results of HBV among the population of childbearing age in Jiangsu Province from 2010 to 2020, and to provide reference for scientific prevention and control of HBV infection. Methods Serological testing results of HBV were collected from 1 061 396 cases (530 698 pairs) of childbearing age population who participated in the national free pre-pregnancy health examination program from 2010 to 2020, and the HBV infection status and influencing factors were analyzed in Jiangsu Province. Results From 2010 to 2020, the total positive rate of HBsAg and HBsAb was 4.49% and 35.82% respectively in Jiangsu Province, and the positive rate of HBsAg and HBsAb showed an downward trend (HBsAg: trend χ² =542.665, P < 0.001; HBsAb: trend χ² =727.147, P < 0.001). The positive rate of HBsAg and HBsAb were statistically significant in different testing years, gender, age groups, educational levels and occupations (all P < 0.001). The positive rate of HBsAb was also statistically significant in different ethnic groups, hepatitis B vaccination status and registered permanent residence (all P < 0.001), but there was no significant difference in the positive rate of HBsAg (P>0.05). Among the couples of childbearing age, 8.33% of husbands or wives whose HBsAg test results was positive alone, while 50.67% of their spouses tested negative for HBsAb. Conclusions The overall HBV infection rate among the population of childbearing age in Jiangsu Province is at the medium level, and the positive rate of HBsAg decreased gradually from 2010 to 2020. However, the overall positive rate of HBsAb is still low, and most people of the childbearing age are susceptible to HBV, especially in the families whose husbands or wives tested positive for HBsAg alone. Cosidering over half of their spouses tested negative for HBsAb, emphasizing the importance of timely hepatitis B vaccination and improving the protection rate of HBsAb.The positive rate of HBsAg is also related to different gender, age groups, educational level, occupation and other factors, it is necessary to formulate targeted prevention and control measures to further consolidate and strengthen the prevention and control effect of HBV.
- Hepatitis B virus,
- Hepatitis B surface antigen,
- Hepatitis B surface antibody,
- Pre-pregnancy health examination

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References(17)

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