-
摘要:
目的 分析新型冠状病毒肺炎(coronavirus disease 2019, COVID-19, 简称“新冠肺炎”)的流行病学特征与部分临床特征,为新冠肺炎的防控提供参考依据。 方法 通过爬虫技术爬取“今日头条”网站发布的新冠肺炎确诊病例及其活动轨迹信息,进行统计分析。 结果 2020年1月8日-2020年2月16日,共收集到病例6 814例,省会及直辖市病例数占15.13%,地级市及县镇病例数占63.98%,农村病例数占比13.41%;新冠肺炎确诊人数呈先增加后减少的趋势;男性确诊患者数量较女性确诊患者数量多5.85%,不同年龄段的性别构成差异有统计学意义(x2 =36.466,P < 0.001);患者年龄中位数为45岁,18~45岁分段人数最多,占44.35%;患者潜伏期中位数为8 d,潜伏期在1~14 d内的患者占86%,不同年龄段分组,男女潜伏期天数的差异均无统计学意义(均有P>0.05)。 结论 人群对新型冠状病毒普遍易感,潜伏期符合一般病毒的规律。由于我国疫情防控措施得当,且传播风险期短,疫情的发展得到遏制。新冠肺炎流行病学特征的研究成果将为我国新冠肺炎新一波疫情防控和复工复学的策略制定提供参考依据。 Abstract:Objective To analyze the epidemiological and clinical characteristics of coronavirus disease 2019 (COVID-19) in order to provide reference for COVID-19 prevention and control. Methods Web-Crawler was used to crawl the information of confirmed COVID-19 cases published on "TouTiao" website for statistical analysis. Results From Jan 8th to Feb 16th, 2020, 6 814 cases were collected on the website. The cases in provincial capitals and municipalities accounted for 15.13%, in prefecture-level cities and counties accounted for 63.98%, and in rural cases accounted for 13.41%. The number of COVID-19 cases was increased at first and then decreased. The number of confirmed cases in males was 5.85% higher than that in females, and there are statistically significant differences in gender composition of different age groups (x2=36.466, P < 0.001). The number of females was higher than that of males. The median age of the patients was 45 years old, and the number of patients aged from 18 to 45 years was the highest (44.35%). The median incubation was 8 days, 86% of the patients were within 1-14 days. There is no significant difference in days of incubation period between males and females in different age groups (all P>0.05). Conclusions People are generally susceptible to COVID-19, and the incubation period is consistent with the pattern of the general virus. Due to the proper measures in China and the short transmission risk period, the epidemic has been contained. The study on the epidemiological characteristics of COVID-19 will provide reference for the strategy formulation of COVID-19 prevention and control and the resumption of work and school in China. -
Key words:
- COVID-19 /
- Epidemic characteristics /
- The crawler technology /
- Network data
-
表 1 新冠肺炎确诊病例基本人口学特征[n(%)]
Table 1. Basic demographic characters of the confirmed cases of COVID-19 [n(%)]
变量 n(例) 性别缺失 男性 女性 x2值 P值 年龄(岁) 36.466 < 0.001 < 7 103(1.51) 2(0.03) 53(0.78) 48(0.70) 7~ 92(1.35) 2(0.03) 47(0.69) 43(0.63) 13~ 82(1.20) 0(0.00) 53(0.78) 29(0.43) 18~ 3 022(44.34) 65(0.95) 1 674(24.57) 1 283(18.83) 46~ 2 710(39.77) 51(0.75) 1 305(19.15) 1 354(19.87) >69 397(5.83) 6(0.09) 204(2.99) 187(2.74) 年龄缺失 408(5.99) 33(0.48) 191(2.80) 184(2.70) 地区 3.095 0.213 省会及直辖市 1 031(15.13) 19(0.28) 521(7.65) 491(7.21) 地级市及县镇 4 360(63.98) 87(1.28) 2 264(33.23) 2 009(29.48) 农村 914(13.41) 40(0.59) 485(7.12) 389(5.71) 地区缺失 509(7.47) 13(0.19) 257(3.77) 239(3.51) 接触史 33.451 < 0.001 常住武汉 1 442(21.16) 42(0.62) 789(11.58) 617(9.05) 路过武汉 61(0.90) 1(0.01) 39(0.57) 21(0.31) 旅居武汉 635(9.32) 11(0.16) 354(5.20) 270(3.96) 到过武汉(时长未知) 266(3.90) 4(0.06) 170(2.49) 92(1.35) 未到过武汉 2 508(36.81) 40(0.59) 1 241(18.21) 1 227(18.01) 接触史缺失 1 902(27.91) 61(0.90) 940(13.80) 901(13.22) -
[1] 武汉市卫生健康委员会.武汉市卫健委关于当前我市肺炎疫情的情况通报[EB/OL]. (2019-12-31)[2020-05-12]. http://wjw.hubei.gov.cn/fbjd/dtyw/201912/t20191231_1822343.shtml.Wuhan Municipal Health Commission. Wuhan Municipal Health Commission's report on the current situation of pneumonia in our city.[EB/OL]. (2019-12-31)[2020-05-12]. http://wjw.hubei.gov.cn/fbjd/dtyw/201912/t20191231_1822343.shtml. [2] 中华人民共和国国家卫生健康委员会.国家卫生健康委关于新型冠状病毒肺炎暂命名事宜的通知[EB/OL]. (2020-02-07)[2020-05-12]. http://www.nhc.gov.cn/xcs/zhengcwj/202002/18c1bb43965a4492907957875de02ae7.National Health Commission of the People's Republic of China. Notice from the National Health Commission on the provisional naming of COVID-19[EB/OL]. (2020-02-07)[2020-05-12]. http://www.nhc.gov.cn/xcs/zhengcwj/202002/18c1bb43965a4492907957875de02ae7. [3] World Health Organization. Rolling updates on coronavirus disease (COVID-19)[EB/OL]. (2020-02-11)[2020-05-12]. https://www.who.int/emergencies/diseases/novel-coronavirus-2019/events-as-they-happen. [4] 湖北省人民政府.武汉市新型冠状病毒感染的肺炎疫情防控指挥部通告(第1号)[EB/OL]. (2020-01-23)[2020-05-12]. http://www.gov.cn/xinwen/2020-01/23/content_5471751.htm.Hubei Provincial People's Government. Notice of the Headquarters for the Prevention and Control of the Novel Coronavirus Pneumonia Epidemic in Wuhan (No. 1)[EB/OL]. (2020-01-23)[2020-05-12]. http://www.gov.cn/xinwen/2020-01/23/content_5471751.htm. [5] 张国磊, 马丽.重大疫情下的农村封闭式治理:情境、过程与结果—基于桂中H村的调研分析[J].西北农林科技大学学报(社会科学版), 2020, 20(3):32-41. DOI: 10.13968/j.cnki.1009-9107.2020.03.04.Zhang GL, Ma L. Closed rural governance in major epidemics: situation, process and results—based on the survey and analysis of H village in Guangxi[J]. Journal of Northwest A&F University (Social Science Edition), 2020, 20(3):32-41. DOI: 10.13968/j.cnki.1009-9107.2020.03.04. [6] Guan W, Ni Z, Hu Y, et al. Clinical characteristics of corona virus disease 2019 in China[J]. N Engl J Med, 2020, 382(18):1708-1720. DOI: 10.1056/NEJMoa2002032. [7] 李陈晨, 马倩倩, 殷环, 等.河南省新型冠状病毒肺炎高发区流行病学特征及防控分析[J].武汉大学学报(医学版), 2020, 41(04):521-528. DOI: 10.14188/j.1671-8852.2020.0113.Li CC, Ma QQ, Yin H, et al. Epidemiological features and prevention measures of COVID-19 in high incidence areas of Henan Province[J]. Medical Med J Wuhan Univ, 2020, 41(04):521-528. DOI: 10.14188/j.1671-8852.2020.0113. [8] Li Q, Guan X, Wu P, et al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia[J]. N Engl J Med, 2020, 382(13):1199-1207. DOI: 10.1056/NEJMoa2001316. [9] Wang W, Tang J, Wei F. Updated understanding of the outbreak of 2019 novel coronavirus (2019-nCoV) in Wuhan, China[J]. J Med Virol, 2020, 92(4):441-447. DOI: 10.1002/jmv.25689. [10] Rothan HA, Byrareddy SN. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak[J]. J Autoimmun, 2020, 109:102433. DOI: 10.1016/j.jaut.2020.102433. [11] Hu Z, Song C, Xu C, et al. Clinical characteristics of 24 asymptomatic infections with COVID-19 screened among close contacts in Nanjing, China[J]. Sci China Life Sci, 2020, 63(5):706-711. DOI: 10.1007/s11427-020-1661-4. [12] Adhikari SP, Meng S, Wu YJ, et al. Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: a scoping review[J]. Infect Dis Poverty, 2020, 9(1):29 DOI: 10.1186/s40249-020-00646-x. [13] 张彦平, 王岚.新型冠状病毒肺炎流行病学特征分析[J].中华流行病学杂志, 2020, 41(2):145-151. DOI: 10.3760/cma.j.issn.0254-6450.2020.02.003.Zhang YP, Wang L. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China[J]. Chin J Epidemiol, 2020, 41(2):145-151. DOI: 10.3760/cma.j.issn.0254-6450.2020.02.003. [14] 施伎蝉, 宁洪叶, 刘赛朵, 等.温州地区65例新型冠状病毒肺炎患者的流行病学及临床特征分析[J].新医学, 2020, 51(5):360-364. DOI: 10.3969/j.issn.0253-9802.2020.05.007.Shi JC, Ning HY, Liu SD, et al. Analysis of clinical and epidemiological characteristics of 65 cases of COVID-19 in Wenzhou[J]. New Chin Med, 2020, 51(5):360-364. DOI: 10.3969/j.issn.0253-9802.2020.05.007. [15] 詹思延, 叶冬青.流行病学[M].北京:人民卫生出版社, 1981:254-258.Zhan SY, Ye DQ. Epidemiology[M]. BeiJing: People's Medical Publishing House, 1981:254-258. [16] 张燕, 周继明, 朱晓红, 等. 1例无症状新型冠状病毒核酸检测阳性是否诊断轻型探讨[J].解放军医学院学报, 2020, 41(2):127. DOI: 10.3969/j.issn.2095-5227.2020.02.009.Zhang Y, Zhou JM, Zhu XH, et al. Discussion on whether 1 asymptomatic COVID-19 virus nucleic acid test positive diagnosis is mild[J]. Acad J Chin PLA Med Sch, 2020, 41(2):127. DOI: 10.3969/j.issn.2095-5227.2020.02.009. [17] 中华人民共和国国家卫生健康委员会.关于印发新型冠状病毒肺炎诊疗方案(试行第八版)的通知[EB/OL]. (2020-08-19)[2020-09-19]. http://www.nhc.gov.cn/xcs/zhengcwj/202008/0a7bdf12bd4b46e5bd28ca7f9a7f5e5a.shtml.National Health Commission of the People's Republic of China. Notice on issuing the diagnosis and treatment plan of COVID-19 (Trial Version 8)[EB/OL]. (2020-08-19)[2020-09-19]. http://www.nhc.gov.cn/xcs/zhengcwj/202008/0a7bdf12bd4b46e5bd28ca7f9a7f5e5a.shtml. [18] 中华人民共和国国家卫生健康委员会.截至2月15日24时新型冠状病毒肺炎疫情最新情况[EB/OL]. (2020-02-16)[2020-05-12]. http://www.nhc.gov.cn/xcs/yqtb/202002/4a1b1ec6c03548099de1c3aa935d04fd.shtml.National Health Commission of the People's Republic of China. The latest situation of COVID-19 as of 24: 00 on February 15[EB/OL]. (2020-02-16)[2020-05-12].http://www.nhc.gov.cn/xcs/yqtb/202002/4a1b1ec6c03548099de1c3aa935d04fd.shtml.