Association between iron deficiency anemia and blood lead level in children: a Meta-analysis

KUANG Man-hua; YANG Qing-ting; JIAN Yao-wen; XIONG Wen-jing; GAO Lu; RANG Wei-qing

doi:10.16462/j.cnki.zhjbkz.2016.01.020

Volume 20 Issue 1

Jan. 2016

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KUANG Man-hua, YANG Qing-ting, JIAN Yao-wen, XIONG Wen-jing, GAO Lu, RANG Wei-qing. Association between iron deficiency anemia and blood lead level in children: a Meta-analysis[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(1): 79-83. doi: 10.16462/j.cnki.zhjbkz.2016.01.020

Citation:

KUANG Man-hua, YANG Qing-ting, JIAN Yao-wen, XIONG Wen-jing, GAO Lu, RANG Wei-qing. Association between iron deficiency anemia and blood lead level in children: a Meta-analysis[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(1): 79-83. doi: 10.16462/j.cnki.zhjbkz.2016.01.020

Citation:

KUANG Man-hua, YANG Qing-ting, JIAN Yao-wen, XIONG Wen-jing, GAO Lu, RANG Wei-qing. Association between iron deficiency anemia and blood lead level in children: a Meta-analysis[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(1): 79-83. doi: 10.16462/j.cnki.zhjbkz.2016.01.020

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Association between iron deficiency anemia and blood lead level in children: a Meta-analysis

doi: 10.16462/j.cnki.zhjbkz.2016.01.020

1. Center for Disease Control and Evaluation, School of Public Health, University of South China, Hengyang 421001, China;
2. Center of Evidence-based Medicine, School of Basic Medicine, Beijing University of Chinese Medicine, Beijing 100000, China

Received Date: 2015-10-02
Rev Recd Date: 2015-12-10

Abstract

Abstract

Objective To analyze and evaluate the relationship between iron deficiency anemia (IDA) and blood lead level (BLL) in children by using Meta-analysis. Methods Chinese and English literature prior to December 2014 on children with blood lead levels of iron deficiency anemia were searched and collected. Stata12.0 was used for data analysis, Cochrane's Q and I² statistics were used to evaluate heterogeneity among studies, subgroup analysis and sensitivity analysis were used to explore the heterogeneity sources. Publication bias was calculated by funnel plot, Begg rank correlation test and Egger linear regression test. Results A total of 7 articles were considered and totally 722 cases of iron deficiency anemia group and 927 cases in control group were enrolled in the study. The combined children's blood lead level of standardization mean difference and 95% confidence intervals SMD (95% CI) was 1.18 (0.57-1.80), the results showed that the group of children with iron deficiency anemia blood lead level was higher and the difference was statistically significant (Z=3.78,P<0.001). Conclusions Our finding suggests that the blood lead level is correlated with the occurrence of IDA, and the average blood lead level of children with IDA is higher than that of the control group.
- Children,
- Anemia,iron deficiency,
- Blood lead level,
- Meta-analysis

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References(25)

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