Analysis of the risk factors of hepatitis B virus infection in hemodialysis patients in Lanzhou

LIU Rui-fang; CHEN Ji-jun; LEI Miao; LI Gang-gang; LI Yuan-lin; SHI Dai-yu; GAO Wen-long; QI Yue-jun

doi:10.16462/j.cnki.zhjbkz.2019.06.017

Volume 23 Issue 6

Jun. 2019

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Article Navigation > CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION > 2019 > 23(6): 706-710, 716

LIU Rui-fang, CHEN Ji-jun, LEI Miao, LI Gang-gang, LI Yuan-lin, SHI Dai-yu, GAO Wen-long, QI Yue-jun. Analysis of the risk factors of hepatitis B virus infection in hemodialysis patients in Lanzhou[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2019, 23(6): 706-710, 716. doi: 10.16462/j.cnki.zhjbkz.2019.06.017

Citation:

LIU Rui-fang, CHEN Ji-jun, LEI Miao, LI Gang-gang, LI Yuan-lin, SHI Dai-yu, GAO Wen-long, QI Yue-jun. Analysis of the risk factors of hepatitis B virus infection in hemodialysis patients in Lanzhou[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2019, 23(6): 706-710, 716. doi: 10.16462/j.cnki.zhjbkz.2019.06.017

Citation:

LIU Rui-fang, CHEN Ji-jun, LEI Miao, LI Gang-gang, LI Yuan-lin, SHI Dai-yu, GAO Wen-long, QI Yue-jun. Analysis of the risk factors of hepatitis B virus infection in hemodialysis patients in Lanzhou[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2019, 23(6): 706-710, 716. doi: 10.16462/j.cnki.zhjbkz.2019.06.017

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Analysis of the risk factors of hepatitis B virus infection in hemodialysis patients in Lanzhou

doi: 10.16462/j.cnki.zhjbkz.2019.06.017

1.
Department of Epidemiology and Biostatistics, School of Public Health, Lanzhou University, Lanzhou 730000, China
2.
STD and AIDS prevention and control institute, Lanzhou municipal center for disease control and prevention, Lanzhou 730030, China

Funds:

Innovation and Entrepreneurship Project for Talent in Lanzhou 2016-RC-32

Innovation and Entrepreneurship Project for Talent in Lanzhou 2017-RC-14

More Information

Corresponding author: QI Yue-jun, E-mail: 529189297@qq.com
Received Date: 2018-12-14
Rev Recd Date: 2019-03-19
Publish Date: 2019-06-10

Abstract

Abstract

Objective To explore the risk factors of hepatitis B virus infection in hemodialysis patients. Methods The patients in hemodialysis center of five hospitals in Lanzhou were interviewed through a questionnaire survey. The data of social demography, medical history, hemodialysis process and laboratory test of HBV were collected and analyzed by univariate and Generalized Estimating Equation (GEE) model analysis. Results Among total 565 investigated hemodialysis patients, 31 were HBV positive, with the infection rate of 5.49%. The result of GEE analysis indicated that using blood products(before 1998:OR=8.077, 95% CI: 3.469-18.803;after 1998:OR=2.678, 95% CI: 1.719-4.170), blood transfusion (before 1998:OR=5.344, 95% CI: 2.212-12.910), dialysis time(OR=1.008, 95% CI: 1.002-1.014), surgical cosmetology(OR=1.954, 95% CI: 1.015-3.766) and poor educational background (OR=3.564, 95% CI: 1.881-6.753) were risk factors of HBV infection in hemodialysis patients. Compared to hemodialysis patients aged 25 years old and younger, those aged 40 years (OR=0.214, 95% CI: 0.064-0.712) and above had a lower HBsAg positive rate. Conclusions Using blood products, blood transfusion before 1998, dialysis time, surgical cosmetology and poor educational background can increase the risk of HBV infection; poor educational background increases the risk of HBV infection in the hemodialysis patients. More attention should be paid on the management and usage of blood and blood products in clinical treatment. Dialysis operation should be standardized and propaganda of HBV prevention should be strengthened.
- Hemodialysis,
- Hepatitis B virus infection,
- Risk factors,
- Generalized estimating equation

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References(18)

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