Effect of pre-pregnancy body mass index and gestational weight gain on birth weight of infants: a prospective cohort study

WANG Ya-wen; FENG Ya-hui; WU San-san; CAI Shu-ya; MA Liang-kun; JIANG Yu

doi:10.16462/j.cnki.zhjbkz.2020.03.013

Volume 24 Issue 3

Jun. 2020

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WANG Ya-wen, FENG Ya-hui, WU San-san, CAI Shu-ya, MA Liang-kun, JIANG Yu. Effect of pre-pregnancy body mass index and gestational weight gain on birth weight of infants: a prospective cohort study[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2020, 24(3): 314-318. doi: 10.16462/j.cnki.zhjbkz.2020.03.013

Citation:

WANG Ya-wen, FENG Ya-hui, WU San-san, CAI Shu-ya, MA Liang-kun, JIANG Yu. Effect of pre-pregnancy body mass index and gestational weight gain on birth weight of infants: a prospective cohort study[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2020, 24(3): 314-318. doi: 10.16462/j.cnki.zhjbkz.2020.03.013

Citation:

WANG Ya-wen, FENG Ya-hui, WU San-san, CAI Shu-ya, MA Liang-kun, JIANG Yu. Effect of pre-pregnancy body mass index and gestational weight gain on birth weight of infants: a prospective cohort study[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2020, 24(3): 314-318. doi: 10.16462/j.cnki.zhjbkz.2020.03.013

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Effect of pre-pregnancy body mass index and gestational weight gain on birth weight of infants: a prospective cohort study

doi: 10.16462/j.cnki.zhjbkz.2020.03.013

1.
School of Public Health, Chinese Academy of Medical Health & Peking Union Medical College, Beijing 100730, China
2.
Department of Gynaecology and Obstetrics, Peking Union Medical College Hospital, Beijing 100730, China

Funds: CAMS Innovation Fund for Medical Sciences(CIFMS)(2019-I2M-2-007)

More Information

Corresponding author: MA Liang-kun, E-mail:maliangkun@pumch.cn; JIANG Yu, E-mail:jiangyu@pumc.edu.cn
Received Date: 2019-10-17
Rev Recd Date: 2020-01-10
Publish Date: 2020-03-10

Abstract

Abstract

Objective To analyze the relationship between pre-pregnancy body mass index(BMI), gestational weight gain(GWG) and the birth weight of infants, and explore the effect of weight change before and during pregnancy on low birth weight(LBW) and macrosomia. Methods Women were enrolled by the Chinese Pregnant Women Cohort Study during first trimester. Each respondent's weight before and during pregnancy and the birth weight of infant were collected after fellow up. Pre-pregnancy BMI was divided into underweight, normal and overweight/obesity groups and GWG was divided into suitable, insufficient and excessive groups. Multivariate Logistic regression was adopted to explore the relationship between pre-pregnancy BMI, GWG and newborn's birth weight. Results Women's pre-pregnancy BMI and GWG were associated with neonatal birth weight(all P < 0.05). Pre-pregnancy overweight or obesity(OR=2.339, 95% CI:1.674-2.282, P < 0.001) and excessive GWG(OR=1.398, 95% CI:1.188-1.978, P=0.048) were shown as risk factors for macrosomia. Insufficient GWG increased LBW risk(OR=1.479, 95% CI:1.461-1.679, P=0.035) while excessive GWG declined LBW risk(OR=0.428, 95% CI:0.225-0.817, P=0.010). Under weight-insufficient GWG was risk factor of LBW(OR=1.335, 95% CI:1.048-2.319, P=0.048) while normal BMI-excessive GWG(OR=1.088, 95% CI:1.016-1.675, P=0.038) and overweight/obesity-excessive GWG(OR=1.498, 95% CI:1.244-2.017, P=0.046) were associated with higher risk of delivering macrosomia. Conclusions Pre-pregnancy BMI and GWG were associated with infant's birth weight and women were suggested to maintain their weight in recommended range before and during pregnancy.
- Body mass index,
- Gestational weight gain,
- Newborn,
- Birth weight

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References(18)

References

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