Correlation between circadian disruption and depressive symptom in male undergraduates in Chongqing

HOU Gui-zhong; LIU Kun; ZHANG Ai-hua; CHEN Qing; CAO Jia

doi:10.16462/j.cnki.zhjbkz.2020.04.007

Volume 24 Issue 4

Jun. 2020

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HOU Gui-zhong, LIU Kun, ZHANG Ai-hua, CHEN Qing, CAO Jia. Correlation between circadian disruption and depressive symptom in male undergraduates in Chongqing[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2020, 24(4): 404-408. doi: 10.16462/j.cnki.zhjbkz.2020.04.007

Citation:

HOU Gui-zhong, LIU Kun, ZHANG Ai-hua, CHEN Qing, CAO Jia. Correlation between circadian disruption and depressive symptom in male undergraduates in Chongqing[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2020, 24(4): 404-408. doi: 10.16462/j.cnki.zhjbkz.2020.04.007

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Correlation between circadian disruption and depressive symptom in male undergraduates in Chongqing

doi: 10.16462/j.cnki.zhjbkz.2020.04.007

HOU Gui-zhong¹,
LIU Kun²,
ZHANG Ai-hua¹,
CHEN Qing^{2
,
,},
CAO Jia^{1, 2
,
,}

1.
Department of Toxicology, School of Public Health, Guizhou Medical University, Guiyang 550025, China
2.
Institute of Toxicology, College of Military Preventive Medicine, Army Military Medical University(Third Military Medical University), Chongqing 400038, China

Funds: National Key R & D Program of China(2017YFC1002001); National Natural Science Foundation of China(81871208)

More Information

Corresponding author: CHEN Qing, E-mail:chenqingforward@gmail.com; CAO Jia, E-mail:caojia1962@126.com
Received Date: 2019-12-20
Rev Recd Date: 2020-02-01
Publish Date: 2020-04-10

Abstract

Abstract

Objective To analyze the association between circadian disruption and depressive symptoms in Chongqing young males. Methods Among 587 male college students in Chongqing, the Chinese version of the Munich chronotype questionnaire(MCTQ) was used to measure social jetlag(an indicator of circadian disruption), mean sleep duration and chronotype, which reflected individual biological clock. Depression symptom was measured using standard score of the Self-rating Depression Scale(SDS). Results The subjects' social jetlag was 0.9(0.5 to 1.3) h. There was a strong correlation between social jetlag and chronotype indicator(correlation coefficient = 0.58, P < 0.001).The social jetlag was positively correlated with the SDS standard score. For every 0.5 hour increase in the social jetlag, the SDS standard score increased by 2.1%(95%CI: 0.5%-3.5%, P= 0.011). Conclusion There is a correlation between social jetlag and SDS standard score, suggesting that circadian disruption may be related to depressive symptom.
- Circadian clock,
- Sleep,
- Munich chronotype questionnaire,
- Depression

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References(23)

References

[1]	Wang R, Liu Y, Xue D, et al. Depressive symptoms among Chinese residents: how are the natural, built, and social environments correlated?[J]. BMC public health, 2019, 19(1): 887. DOI: 10.1186/s12889-019-7171-9.
[2]	Qin X, Wang S, Hsieh CR. The prevalence of depression and depressive symptoms among adults in China: estimation based on a national household survey[J]. China Economic Review, 2018, (51): 271-282. DOI: 10.1016/j.chieco.2016.04.001.
[3]	王婷, 周艳辉, 罗阳.湖南省青春期女性焦虑、抑郁现状调查及其影响因子的预测[J].中华疾病控制杂志, 2019, 23(8): 971-976. DOI: 10.3760/cma.j.issn.1674-6554.2000.03.016. Wang T, Zhou YH, Luo Y. Anxiety, depression status of adolescent females and prediction of related influencing factors in Hunan Province[J]. Chin J Dis Prev, 2019, 23(8): 971-976. DOI: 10.3760/cma.j.issn.1674-6554.2000.03.016.
[4]	Takahashi JS, Hong HK, Ko CH, et al. The genetics of mammalian circadian order and disorder: implications for physiology and disease[J]. Nat Rev Genet, 2008, 9(10): 764-775. DOI: 10.1038/nrg2430.
[5]	Bunney WE, Bunney BG. Molecular clock genes in man and lower animals: possible implications for circadian abnormalities in depression[J]. Neuropsychopharmacology, 2000, 22(4): 335-345. DOI: 10.1016/S0893-133X(99)00145-1.
[6]	Landgraf D, Long JE, Welsh DK. Depression-like behaviour in mice is associated with disrupted circadian rhythms in nucleus accumbens and periaqueductal grey[J]. Eur J neurosci, 2016, 43(10): 309-320. DOI: 10.1111/ejn.13085.
[7]	Griesauer I, Diao W, Ronovsky M, et al. Circadian abnormalities in a mouse model of high trait anxiety and depression[J]. Ann Med, 2014, 46(3): 148-154. DOI: 10.3109/07853890.2013.866440.
[8]	Levandovski R, Dantas G, Fernandes LC, et al. Depression scores associate with chronotype and social jetlag in a rural population[J]. Chronobiol Int, 2011, 28(9): 771-778. DOI: 10.3109/07420528.2011.602445.
[9]	De Souza CM, Hidalgo MP. Midpoint of sleep on school days is associated with depression among adolescents[J]. Chronobiol Int, 2014, 31(2): 199-205. DOI: 10.3109/07420528.2013.838575.
[10]	Knapen, SE, Riemersma-van der Lek RF, Antypa N, et al. Social jetlag and depression status: results obtained from the Netherlands study of depression and anxiety[J]. Chronobiol Int, 2018, 35(1): 1-7. DOI: 10.1080/07420528.2017.1374966.
[11]	Roenneberg T, Wirz-Justice A, Merrow, M. Life between clocks: daily temporal patterns of human chronotypes[J]. J Biol Rhythms, 2003, 18(1): 80-90. DOI: 10.1177/0748730402239679.
[12]	Roenneberg T, Pilz LK, Zerbini G, et al. Chronotype and social jetlag: a(self)-ritical review[J]. Biology, 2019, 8(3): 54. DOI: 10.3390/biology8030054.
[13]	Zou P, Wang X, Sun L, et al. Semen quality in Chinese college students: associations with depression and physical activity in a cross-sectional study[J]. Psychosom Med, 2018, 80(6): 564-572. DOI: 10.1097/PSY.0000000000000595.
[14]	陈卿.睡眠行为、昼夜节律与男(雄)性精液参数的关联研究[D].重庆: 第三军医大学, 2015. Chen Q. Association among sleep behaviors, circadian system and semen parameters in males[D]. Chongqing: Third Military Medical University, 2015.
[15]	Roenneberg T, Allebrandt KV, Merrow M, et al. Social jetlag and obesity[J]. Curr Biol: CB, 2012, 22(10): 939-943. DOI: 10.1016/j.cub.2012.03.038.
[16]	Gamble KL, Motsinger-Reif AA, Hida A, et al. Shift work in nurses: contribution of phenotypes and genotypes to adaptation[J]. PLoS One, 2011, 6(4): e18395. DOI: 10.1371/journal.pone.0018395.
[17]	Kim HI, Lee HJ, Cho CH, et al. Association of CLOCK, ARNTL, and NPAS2 gene polymorphisms and seasonal variations in mood and behavior[J]. Chronobiol Int, 2015, 32(6): 785-791. DOI: 10.3109/07420528.2015.1049613.
[18]	Bellivier F, Geoffroy PA, Etain B, et al. Sleep-and circadian rhythm-associated pathways as therapeutic targets in bipolar disorder[J]. Expert Opin Ther Targets, 2015, 19(6): 747-763. DOI: 10.1517/14728222.2015.1018822.
[19]	Salgado-Delgado R, Tapla Osorio A, Saderi N, et al. Disruption of circadian rhythms: a crucial factor in the etiology of depression[J]. Depress Res Treat, 2011, 2011: 1-9. DOI: 10.1155/2011/839743.
[20]	Gouin JP, Connors J, Kiecolt-Glaser JK, et al. Altered expression of circadian rhythm genes among individuals with a history of depression[J]. J Affect Disord, 2010, 126(1-2): 161-166. DOI: 10.1016/j.jad.2010.04.002.
[21]	Zhang Z, Cajochen C. Social jetlag and chronotypes in the Chinese population: analysis of data recorded by wearable devices[J]. J Med Internet Res, 2019, 21(6): e13482. DOI: 10.2196/13482.
[22]	Wittmann M, Dinich J, Merrow M, et al. Social jetlag: misalignment of biological and social time[J]. Chronobiol Int, 2006, 23(1-2): 497-509. DOI: 10.1080/07420520500545979.
[23]	Zavada A, Gordijn MC, Beersma DG, et al. Comparison of the munich chronotype questionnaire with the Horne-Ostberg's morningness-eveningness score[J]. Chronobiol Int, 2005, 22(2): 267-278. DOI: 10.1081/cbi-200053536.