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CN 34-1304/RISSN 1674-3679

Volume 25 Issue 4
May  2021
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ZHAO De-sheng, BAO Ping, CHENG Jian, WANG Xu, FANG Shi-yuan, SU Hong. Association of schizophrenia onset with exposure to outdoor thermal comfort: effect modification by individual characteristics[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(4): 460-465. doi: 10.16462/j.cnki.zhjbkz.2021.04.016
Citation: ZHAO De-sheng, BAO Ping, CHENG Jian, WANG Xu, FANG Shi-yuan, SU Hong. Association of schizophrenia onset with exposure to outdoor thermal comfort: effect modification by individual characteristics[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(4): 460-465. doi: 10.16462/j.cnki.zhjbkz.2021.04.016

Association of schizophrenia onset with exposure to outdoor thermal comfort: effect modification by individual characteristics

doi: 10.16462/j.cnki.zhjbkz.2021.04.016
Funds:

National Natural Science Fundation of China 8177120532

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  • Corresponding author: SU Hong, E-mail: fangshiyuan2008@126.com; FANG Shi-yuan, E-mail: suhong5151@sina.com
  • Received Date: 2020-02-12
  • Rev Recd Date: 2021-01-11
  • Available Online: 2021-05-11
  • Publish Date: 2021-04-10
  •   Objective  To investigate the association between exposure to high humidex and the risk of schizophrenia onset.  Methods  Daily schizophrenia and meteorological data from 1 January 2005 to 31 December 2014 in Hefei, China, were collected. We quantified the relationship between humidex and schizophrenia onset using a distributed lag nonlinear model (DLNM). The effect modifications by gender, age, marital status and study periods were also examined.  Results  High humidex was significantly associated with schizophrenia onset, with the largest effect at two days lag (RR=1.031, 95% CI: 1.011-1.051, P < 0.05). When conducting subgroup analyses by individuals characteristics, we found that patients aged 21-60 years, males and married patients were more vulnerable to high humidex than patients aged 0-20, ≥60 years, females and unmarried patients, respectively. In addition, we also observed a clear decline in the effect of high humidex on schizophrenia from the first five years (2005-2009) to the second five years (2010-2014).  Conclusion  This study suggested that high humidex was a risk factor for schizophrenia onset, and patients aged 21-60 years, males and married patients were particularly vulnerable to the effect of high humidex.
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