Joint frailty models for zero-inflated analysis of different outcomes in patients with coronary heart disease complicated with chronic heart failure

LI Jing; TIAN Jing; YAN Jing-jing; REN Jia; HAN Qing-hua; ZHANG Yan-bo

doi:10.16462/j.cnki.zhjbkz.2021.08.016

Volume 25 Issue 8

Aug. 2021

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Article Navigation > CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION > 2021 > 25(8): 962-967

LI Jing, TIAN Jing, YAN Jing-jing, REN Jia, HAN Qing-hua, ZHANG Yan-bo. Joint frailty models for zero-inflated analysis of different outcomes in patients with coronary heart disease complicated with chronic heart failure[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(8): 962-967. doi: 10.16462/j.cnki.zhjbkz.2021.08.016

Citation:

LI Jing, TIAN Jing, YAN Jing-jing, REN Jia, HAN Qing-hua, ZHANG Yan-bo. Joint frailty models for zero-inflated analysis of different outcomes in patients with coronary heart disease complicated with chronic heart failure[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(8): 962-967. doi: 10.16462/j.cnki.zhjbkz.2021.08.016

Citation:

LI Jing, TIAN Jing, YAN Jing-jing, REN Jia, HAN Qing-hua, ZHANG Yan-bo. Joint frailty models for zero-inflated analysis of different outcomes in patients with coronary heart disease complicated with chronic heart failure[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(8): 962-967. doi: 10.16462/j.cnki.zhjbkz.2021.08.016

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Joint frailty models for zero-inflated analysis of different outcomes in patients with coronary heart disease complicated with chronic heart failure

doi: 10.16462/j.cnki.zhjbkz.2021.08.016

LI Jing^{1, 2},
TIAN Jing³,
YAN Jing-jing^{1, 2},
REN Jia³,
HAN Qing-hua^{3
,
,},
ZHANG Yan-bo^{1, 2
,
,}

1.
Department of Biostatistics, School of Public Health, Shanxi Medical University, Taiyuan 030000, China
2.
Department of Cardiology, First Affiliated Hospital, Shanxi Medical University, Taiyuan 030000, China
3.
Shanxi Provincial Key Laboratory of Major Diseases Risk Assessment, Taiyuan 030000, China

Funds:

National Natural Science Foundation of China 81872714

Shanxi Provincial Key Laboratory 201805D111006

More Information

Corresponding author: HAN Qing-hua, E-mail: syhqh@sohu.com; ZHANG Yan-bo, E-mail: sxmuzyb@126.com
Received Date: 2020-12-09
Rev Recd Date: 2021-02-27

Available Online: 2021-08-24

Publish Date: 2021-08-10

Abstract

Abstract

Objective Joint frailty models for zero-inflated was established to explore the influential factors of different outcomes for patients with coronary heart disease complicated with chronic heart failure to reduce the incidence of adverse outcomes. Methods The sample includes patients with coronary heart disease complicated with chronic heart failure in two tertiary hospitals of Shanxi Province from 2014 to 2015. The electronic medical record information of patients during hospitalization and their follow-up information were collected, and joint frailty models for zero-inflated was established to analyze the influential factors. Results A total of 2 221 patients were included in this study. 1 312 patients had no incident (59.07%), 669 patients were re-hospitalized (31.47%) and 307 patients died (13.82%). Gender, occupation and BMI were common influential factors for different outcomes of patients with coronary heart disease complicated with chronic heart failure. Old myocardial infarction and prolonged QRS interval were influential factors to reduce the possibility of patients not being hospitalized again. Advanced age, NYHA grade ≥ Ⅲ and valvular disease were risk factors for rehospitalization and death. Prolonged QRS interval was a risk factor of death; on the contrary, coronary artery bypass grafting was a protective factor to reduce mortality. Conclusions Joint frailty models for zero-inflated can analyze the influential factors of non-rehospitalization, rehospitalization and death for patients with coronary heart disease complicated with chronic heart failure simultaneously, and provide a theoretical reference for the identification, intervention and treatment of high-risk patients.
- Chronic heart failure,
- Rehospitalization,
- Death,
- Joint frailty models for zero-inflated

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References(29)

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