中华疾病控制杂志

Research advances in the epidemiology of autoimmune diseases

FANG Xin-yu, LENG Rui-xue, FAN Yin-guang, ZHANG Qin, PAN Hai-feng, YE Dong-qing

2021, 25(8): 869-873. doi: 10.16462/j.cnki.zhjbkz.2021.08.001

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Autoimmune diseases (AIDs) are a heterogeneous group of diseases characterized by the loss of self-tolerance, which leads to prolonged inflammation and subsequent tissue damage. The exact etiology and pathogenesis of this type of disease have not been fully elucidated. As incurable diseases, AIDs si...

Identifying rheumatoid diseases-associated gut microbiota using microbiota-related gene set enrichment analysis

HE Pei, WANG Man-li, CAO Rong-rong, DONG Chen-yue, DENG Fei-yan, LEI Shu-feng

2021, 25(8): 874-878,986. doi: 10.16462/j.cnki.zhjbkz.2021.08.002

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Objective This study aims to detect the association between gut microbiota and rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and ankylosing spondylitis (AS). Methods The microbiota-related gene set enrichment analysis (GSEA) was applied to identify rheumatoid diseases-related gut mic...

Research advance on the role of meteorological factors in inflammatory immune diseases

CHEN Yue, LENG Rui-xue, PAN Hai-feng

2021, 25(8): 879-884,992. doi: 10.16462/j.cnki.zhjbkz.2021.08.003

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With the intensification of global climate change and human activities, the role of environmental factors in human health is gradually highlighted. Air pollution and meteorological factors, as the main components of environmental factors, have attracted widespread attention to their impact on human ...

Epidemic trend and spatial distribution characteristics of gonorrhea in Mainland China from 2014 to 2018

YU Li, WANG Yi-hui, WANG Peng-ju, YUAN Yan, CAO Yan-wen, LI Shao-xuan, GAO Yin-yan, DING Guo-wu

2021, 25(8): 885-890,954. doi: 10.16462/j.cnki.zhjbkz.2021.08.004

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Objective To explore the epidemic trend and spatial distribution characteristics of gonorrhea in Mainland China from 2014 to 2018, and provide reference for identifying key prevention areas and formulating targeted prevention and control strategies. Methods Based on the data of gonorrhea from online...

Study on the relationship between early clinical symptoms and prognosis of Japanese encephalitis: based on Group LASSO Logistic regression model

LIU Yan-chen, ZHANG Xiao-shu, CUI Xu-dong, JIN Na, ZHAO Xiang-kai, ZHAO Xin, ZHENG Hong-miao, LI Juan-sheng, SHEN Xi-ping, MENG Lei, REN Xiao-wei

2021, 25(8): 891-897,934. doi: 10.16462/j.cnki.zhjbkz.2021.08.005

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Objective To explore the application of Group least absolute shrinkage and selection operator (LASSO) Logistic regression model in the study of the relationship between early clinical symptoms and prognosis of Japanese encephalitis (JE). Methods The data on JE in Gansu Province between 2017 to 2018 ...

Temporal-spatial clustering analysis of pulmonary tuberculosis in Beijing from 2015 to 2019

LIU Yang, GAO Yan-lin, SHI Yun-ping, WANG Chao, XIE Chun-yan, HU Xiao

2021, 25(8): 898-904. doi: 10.16462/j.cnki.zhjbkz.2021.08.006

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Objective To understand the spatial and temporal distributions and the clustering areas of pulmonary tuberculosis in Beijing from 2015 to 2019, and to provide evidence for the disease prevention and control. Methods Descriptive epidemiologic methods were used to analyze pulmonary tuberculosis data i...

A dynamical model study on the transmission of COVID-19 in Urumqi City

LIAO Ying, ZHANG Xue-liang, JIAO Hai-yan, WANG Lei

2021, 25(8): 905-911, 922. doi: 10.16462/j.cnki.zhjbkz.2021.08.007

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Objective To fit the epidemic situation of COVID-19 in Urumqi City, Xinjiang Uygur Autonomous Region in July 2020, so as to provide the quantitative and theoretical basis for the prevention and control of epidemic. Methods A dynamical model with stage control strategy was proposed using compartmenta...

A report on vector surveillance in Guangzhou from 2017 to 2019

HE Tao, LI Xiao-ning, CHEN Zong-qiu, JIANG Yi-min, LIU Jie, Wang Xiu-juan, YANG Zhi-cong

2021, 25(8): 912-917. doi: 10.16462/j.cnki.zhjbkz.2021.08.008

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Objective To understand the composition, density and seasonal fluctuation of vector populations in Guangzhou in recent years, so as to provide scientific basis for vector control. Methods According to the "National Vector Monitoring Program" and "Guangzhou Vector Monitoring Program", a monthly monit...

Investigation on infectious disease-specific health literacy of Chinese expatriates in engineering construction enterprises

XIE Yan, ZHANG Xue-jun, XIE Zheng, HUANG Yang-mu

2021, 25(8): 918-922. doi: 10.16462/j.cnki.zhjbkz.2021.08.009

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Objective To investigate the infectious disease-specific health literacy (IDSHL) level of Chinese expatriates in engineering construction enterprises and its influencing factors, providing evidence-based recommendation for infection prevention and control practices. Methods A cluster sampling design...

Smoking affects the development of rheumatoid arthritis through the IRF4 signaling pathway

LIANG Xin-tong, QIAN Long, CHENG Lin, LI Dong-xu, XU Zhou-zhou

2021, 25(8): 923-927,961. doi: 10.16462/j.cnki.zhjbkz.2021.08.010

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Objective To compare the expression levels of interferon regulatory factor 4 (IRF4) and Rho-associated protein kinase 2 (ROCK2) mRNA in peripheral blood mononuclear cell (PBMC) of smoking and non-smoking rheumatoid arthritis (RA) patients and healthy control (HC) subjects, and to investigate whether...

Identification for biomarkers of skin lesions and lupus nephritis in patients with systemic lupus erythematosus

XIA Yuan-rui, FAN Yin-guang, FANG Xin-yu, YE Dong-qing

2021, 25(8): 928-934. doi: 10.16462/j.cnki.zhjbkz.2021.08.011

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Objective To explore protein biomarkers of skin lesions and lupus nephritis (LN) in patients with systemic lupus erythematosus (SLE), so as to provide evidence for diagnosis and control of the SLE. Methods High-throughput protein chip technology was used to identify serum protein biomarkers for SLE,...

Diagnostic value of IP-10 in rheumatoid arthritis: a systematic review and Meta-analysis

LI Qing-ru, FANG Xin-yu, XIA Yuan-rui, GUO Heng-sheng, WANG Jun-ping, MAO Yan-mei, SHUAI Zong-wen, YE Dong-qing

2021, 25(8): 935-942. doi: 10.16462/j.cnki.zhjbkz.2021.08.012

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Objective We aimed to analyze the changes of interferon-inducible protein 10 (IP-10) in rheumatoid arthritis (RA) and evaluate the diagnostic value of IP-10 in RA and its correlation with disease activity. Methods We collected articles related to our research topic through an electronic literature s...

Role of RIPK1 in the pathogenesis of rheumatoid arthritis and analysis of its geneticsusceptibility

LI Xin-ya, LIU Ya-lin, TANG Yu-jie, LI Xiao-lin, TAO Jin-hui

2021, 25(8): 943-947. doi: 10.16462/j.cnki.zhjbkz.2021.08.013

Abstract(784)

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Objective To analyze the role of receptor interacting protein kinase 1 (RIPK1) in the pathogenesis of rheumatoid arthritis (RA) and exploring the association between gene polymorphism and genetic susceptibility to RA. Methods The mRNA level of RIPK1 in peripheral blood mononuclear cells (PBMC) of RA...

Analysis of healthy lifestyle status of 22 083 high-risk populations of cardiovascular disease in Jiangsu Province

PAN Zi-rui, SUN Zhong-ming, WEN Jin-bo, QIN Yu, SU Jian, CUI Lan, ZHOU Jin-yi, WU Ming, TAO Ran

2021, 25(8): 948-954. doi: 10.16462/j.cnki.zhjbkz.2021.08.014

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Objective To investigate the distribution characteristics of healthy lifestyle in urban and rural high-risk populations of cardiovascular disease (CVD)in Jiangsu Province. Methods Based on the data of national CVD screening and comprehensive intervention project during 2015-2018 in Jiangsu Province,...

Study on the association between pulse pressure and renal function decline among middle-aged and elderly people

YANG Xue-ying, TIAN Jing, DAI Qiao-yun, WANG Yong-hong, ZHANG Jun-hui, JIAO Kai-lei, MA Xu, ZHAO Jun

2021, 25(8): 955-961. doi: 10.16462/j.cnki.zhjbkz.2021.08.015

Abstract(504)

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Objective To explore the association between pulse pressure (PP) and renal function decline among middle-aged and elderly people. Methods A total of 46 605 middle-aged and elderly people (aged ≥45 years old) who participated in the physical examination in the First Affiliated Hospital of Chongqing M...

Joint frailty models for zero-inflated analysis of different outcomes in patients with coronary heart disease complicated with chronic heart failure

LI Jing, TIAN Jing, YAN Jing-jing, REN Jia, HAN Qing-hua, ZHANG Yan-bo

2021, 25(8): 962-967. doi: 10.16462/j.cnki.zhjbkz.2021.08.016

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Objective Joint frailty models for zero-inflated was established to explore the influential factors of different outcomes for patients with coronary heart disease complicated with chronic heart failure to reduce the incidence of adverse outcomes. Methods The sample includes patients with coronary he...

Analysis of factors associated with diabetes mellitus in Shanxi Province based on Bayesian network model

WANG Xu-chun, ZHAI Meng-meng, REN Hao, LI Mei-chen, QUAN Di-chen, ZHANG Jie, CHEN Li-min, QIU Li-xia

2021, 25(8): 968-974. doi: 10.16462/j.cnki.zhjbkz.2021.08.017

Abstract(904)

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Objective For the survey data on diabetes in Shanxi Province in 2015, a Bayesian network model of diabetes-related factors was constructed using the max-min hill-climbing (MMHC) algorithm to explore the network relationships between diabetes and its related factors, and the strength of each influenc...

Relationship between medium-chain saturated fatty acids and risk of oral cancer

SU Jue, LI Yan-ni, FAN Yi, WANG Si-jie, XU Ming-ming, ZHOU Nan, HE Qi-xuan, YU Dao-xuan, LYU Ji-rong, CHEN Qing, WANG Jing, SHI Bin, QIU Yu, LIN Li-song, ZHENG Xiao-yan, PAN Li-zhen, CHEN Fa, HE Bao-chang, LIU Feng-qiong

2021, 25(8): 975-980. doi: 10.16462/j.cnki.zhjbkz.2021.08.018

Abstract(532)

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Objective To investigate the association between dietary medium-chain saturated fatty acids and the risk of oral cancer. Methods A case-control study was conducted in 225 patients with diagnosed oral cancer and 527 controls. All participants were recruited from the First Affiliated Hospital of Fujia...

Prevalence and development of mental disability in mega cities in China

LUO Ya-nan, PANG Li-hua, GUO Chao, ZHENG Xiao-ying

2021, 25(8): 981-986. doi: 10.16462/j.cnki.zhjbkz.2021.08.019

Abstract(469)

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Objective To study the prevalence and the historical development trend of mental disability in mega cities in China. Methods Using the Second National Disability Sample Survey in 2006, this study analyzed the demographic characteristics and the prevalence of mental disability in inner city areas and...

Study on iodine nutritional status of residents with different water iodine concentrations in areas supplying non-iodized salt

XU Xian, YU Chen, TIAN Cui-cui, XU Shu-dong, LIU Ting-ting, LI Wei-dong

2021, 25(8): 987-992. doi: 10.16462/j.cnki.zhjbkz.2021.08.020

Abstract(581)

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Objective To explore the scope of non-iodized salt supply, and to investigate the iodine nutritional status of residents in non-iodized salt supply areas. Methods The urinary iodine level, thyroid volume and nodules, thyroid hormones and antibodies of adults aged 18- < 60, children aged 8- < 1...

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2021 Vol. 25, No. 8

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Editor

Editor-in-Chief Ye Dongqing M.D.

Assistant editor Fan Yinguang M.D.

Assistant editor Pan Haifeng M.D.

Assistant editor