Effects of ozone concentration on allergic skin disease visits in summer in Hefei from 2015 to 2018

FANG Lan-lan; WU Jun; DENG Li-jun; LIAO Tao; YE Dong-qing; PAN Gui-xia

doi:10.16462/j.cnki.zhjbkz.2022.06.016

Volume 26 Issue 6

Jun. 2022

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Article Navigation > CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION > 2022 > 26(6): 709-714

FANG Lan-lan, WU Jun, DENG Li-jun, LIAO Tao, YE Dong-qing, PAN Gui-xia. Effects of ozone concentration on allergic skin disease visits in summer in Hefei from 2015 to 2018[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(6): 709-714. doi: 10.16462/j.cnki.zhjbkz.2022.06.016

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FANG Lan-lan, WU Jun, DENG Li-jun, LIAO Tao, YE Dong-qing, PAN Gui-xia. Effects of ozone concentration on allergic skin disease visits in summer in Hefei from 2015 to 2018[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(6): 709-714. doi: 10.16462/j.cnki.zhjbkz.2022.06.016

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Effects of ozone concentration on allergic skin disease visits in summer in Hefei from 2015 to 2018

doi: 10.16462/j.cnki.zhjbkz.2022.06.016

Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Hefei 230032, China

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Corresponding author: YE Dong-qing, E-mail: anhuiydq@126.com; PAN Gui-xia, E-mail: pgxkd@163.com
Received Date: 2021-09-08
Rev Recd Date: 2022-01-16

Available Online: 2022-06-16

Publish Date: 2022-06-10

Abstract

Abstract

Objective To investigate the relationship between ozone (O₃) concentration and allergic skin disease (ASD) visits in summer. Methods The daily counts of ASD admissions from January 1, 2015, to December 31, 2018 in summer (every year from June 1st to August 31st) were collected from the First Affiliated Hospital of Anhui Medical University and the First Affiliated Hospital of University of Science and Technology of China, and air pollutants and meteorological data were gathered during the same period. The exposure-lag-response relationship between O₃ concentration and ASD admissions was evaluated using the distributed lag non-linear model (DLNM), in which confounding factors, time trend, day of week, and holiday were adjusted. Results A total of 31 741 ASD admissions were collected during the study period. O₃ concentration was positively correlated with ASD admissions and chronic urticaria admissions but had no statistical significance with atopic dermatitis admissions. When O₃ concentration increased by 10 μg/m³, the maximum single-day lagged effect of ASD admissions was 1.007 (RR=1.007, 95% CI: 1.003-1.011, lag 7 d), and the maximum cumulative lagged effect of ASD admissions was 1.078 (RR=1.078, 95% CI: 1.028-1.131, lag 0-14 d). In males, < 18 years and 18- < 65 years ASD patients, the single-day and cumulative lagged effects of O₃ concentration increased by 10 μg/m³ on ASD admissions were statistically significant (all P < 0.05). Conclusions High concentration O₃ is an important risk factor with lagged effect for ASD in summer in Hefei. The relevant departments should intensify the prevention and control of O₃ pollution in summer, strengthen the medical service for ASD patients and protect the susceptible population.
- Ozone,
- Allergic skin disease,
- Summer,
- Distributed lag non-linear model

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References(25)

References

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