The influencing factors and perinatal outcomes of gestational diabetes

MENG Yao-han; QU Yi-min; ZHAN Yong-le; CHEN Yun-li; SHI Ying-jie; JING Ao; MA Liang-kun; JIANG Yu

doi:10.16462/j.cnki.zhjbkz.2022.09.005

Volume 26 Issue 9

Sep. 2022

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Article Navigation > CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION > 2022 > 26(9): 1011-1016

MENG Yao-han, QU Yi-min, ZHAN Yong-le, CHEN Yun-li, SHI Ying-jie, JING Ao, MA Liang-kun, JIANG Yu. The influencing factors and perinatal outcomes of gestational diabetes[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(9): 1011-1016. doi: 10.16462/j.cnki.zhjbkz.2022.09.005

Citation:

MENG Yao-han, QU Yi-min, ZHAN Yong-le, CHEN Yun-li, SHI Ying-jie, JING Ao, MA Liang-kun, JIANG Yu. The influencing factors and perinatal outcomes of gestational diabetes[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(9): 1011-1016. doi: 10.16462/j.cnki.zhjbkz.2022.09.005

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The influencing factors and perinatal outcomes of gestational diabetes

doi: 10.16462/j.cnki.zhjbkz.2022.09.005

1.
Department of Epidemiology and Biostatistics, School of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
2.
School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China
3.
Institute of Medical Information, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100020, China
4.
Institute of Laboratory Animals Science, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
5.
Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China

Funds:

CAMS Innovation Fund of Medical Sciences (CIFMS) 2019-I2M-2-007

More Information

Corresponding author: JIANG Yu, E-mail: jiangyu@pumc.edu.cn
Received Date: 2022-02-24
Rev Recd Date: 2022-05-24

Available Online: 2022-09-17

Publish Date: 2022-09-10

Abstract

Abstract

Objective To analyze the risk factors of gestational diabetes mellitus (GDM) and to explore the perinatal outcomes of GDM. Methods Data were derived from the Chinese Pregnant Women Cohort Study, and 3 874 pregnant women were included. According to the results of 75 g oral glucose tolerance test, 494 cases were in the GDM group, and 3 380 cases were in the non-GDM group. The clinical characteristics, perinatal outcomes and neonatal outcomes of mothers and infants in each group were recorded, and the data were compared by χ² test, Wilcoxon rank sum test, Fisher exact probability method and univariate logistic regression analysis. Results The incidence of premature delivery and premature rupture of membranes of GDM were higher than those in the normal group, with statistically significant differences (all P < 0.05). The multivariate logistic regression showed that the risk of developing GDM increased with age. In addition, the southern region (OR=1.719, 95% CI: 1.401-2.109, P < 0.001), insufficient weight gain during pregnancy (OR=1.485, 95% CI: 1.164-1.893, P=0.001) and preconception overweight (OR=1.634, 95% CI: 1.241-2.151, P < 0.001) were independent risk factors of GDM. Conclusion Advanced age, southern region, overweight before pregnancy and insufficient weight gain during pregnancy are influencing factors of GDM. The related risk factors should be identified as soon as possible and actively intervened, in order to reduce the occurrence of adverse pregnancy outcomes and improve health status of mothers and infants.
- Gestational diabetes mellitus,
- Perinatal outcomes,
- Influencing factors

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References(20)

References

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