The investigation of minerals in human breast milk across lactation stages in six representative areas of China

QIAN Chang-li; TIAN Fang; CHEN Rui-di; LI Na; MAO Ying-yi; LU Pan-ting; ZHAO Yan-rong; WANG Yu

doi:10.16462/j.cnki.zhjbkz.2022.09.009

Volume 26 Issue 9

Sep. 2022

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QIAN Chang-li, TIAN Fang, CHEN Rui-di, LI Na, MAO Ying-yi, LU Pan-ting, ZHAO Yan-rong, WANG Yu. The investigation of minerals in human breast milk across lactation stages in six representative areas of China[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(9): 1037-1042. doi: 10.16462/j.cnki.zhjbkz.2022.09.009

Citation:

QIAN Chang-li, TIAN Fang, CHEN Rui-di, LI Na, MAO Ying-yi, LU Pan-ting, ZHAO Yan-rong, WANG Yu. The investigation of minerals in human breast milk across lactation stages in six representative areas of China[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(9): 1037-1042. doi: 10.16462/j.cnki.zhjbkz.2022.09.009

Citation:

QIAN Chang-li, TIAN Fang, CHEN Rui-di, LI Na, MAO Ying-yi, LU Pan-ting, ZHAO Yan-rong, WANG Yu. The investigation of minerals in human breast milk across lactation stages in six representative areas of China[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(9): 1037-1042. doi: 10.16462/j.cnki.zhjbkz.2022.09.009

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The investigation of minerals in human breast milk across lactation stages in six representative areas of China

doi: 10.16462/j.cnki.zhjbkz.2022.09.009

1.
Institute of Nutrition and Food Hygiene, School of Public Health, Lanzhou University, Lanzhou 730000, China
2.
Abbott Nutrition Research and Development Center, Shanghai 200233, China

More Information

Corresponding author: ZHAO Yan-rong, E-mail: linda.zhao@abbott.com; WANG Yu, E-mail: wangyu@lzu.edu.cn
Received Date: 2021-11-14
Rev Recd Date: 2022-05-18

Available Online: 2022-09-17

Publish Date: 2022-09-10

Abstract

Abstract

Objective The study aimed to investigate the representative mineral levels in breast milk at different lactation stages in China and to provide reference and guidance for future infant formula development. Methods A total of 690 healthy parturients at different lactation stages were recruited in Chengdu, Shanghai, Tianjin, Guangzhou, Changchun, and Lanzhou. Milk was collected from parturients at 0-5 d, 10-14 d, 40-45 d, 200-240 d, and 300-400 d after delivery. Determination of 12 minerals (K, Ca, Na, Mg, P, Fe, Cu, Zn, Se, Mn, Mo and Cr) in breast milk was conducted by inductively coupled plasma-mass spectrometry (ICP-MS). Results Across the 5 lactation periods, Zn dropped dramatically (about 90%) (all P < 0.05). Minerals including K, Na, Zn, Fe, Cu, and Se were significantly affected by lactation time and tended to decrease with the prolonging of lactation time (all P < 0.05), while being stable after 200 days. Ca and P were stable at the early stage and then decreased slightly at the middle-late lactation stage. The content of Mg stayed stable over the lactation period. Except for Ca, P, Cu, and Mg, other minerals showed no significant regional difference (all P > 0.05). Conclusions There were differences in the mineral content of breast milk at different lactation stages and different regions. Infant formula should consider the representative levels of mineral content in Chinese breast milk, and be developed according to the nutritional needs of infants at different lactation stages. Meanwhile, the mineral absorption and utilization ratio should be improved to make it more similar to breast milk, so as to meet the growth and development needs of infants without increasing the burden on their kidneys.
- Chinese breast milk,
- Mineral content,
- Different lactation periods,
- Different regions

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References(35)

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