Study on the relationship between reduced short-term memory and peripheral blood Aβ<sub>1-42</sub> protein concentration in occupationally people who were exposed to 50 Hz power frequency electromagnetic field

BIAN Hong-ying; ZHANG Yao; WANG Yan; DONG Yi-wen; YE Meng

doi:10.16462/j.cnki.zhjbkz.2022.11.015

Volume 26 Issue 11

Nov. 2022

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BIAN Hong-ying, ZHANG Yao, WANG Yan, DONG Yi-wen, YE Meng. Study on the relationship between reduced short-term memory and peripheral blood Aβ1-42 protein concentration in occupationally people who were exposed to 50 Hz power frequency electromagnetic field[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(11): 1326-1331. doi: 10.16462/j.cnki.zhjbkz.2022.11.015

Citation:

BIAN Hong-ying, ZHANG Yao, WANG Yan, DONG Yi-wen, YE Meng. Study on the relationship between reduced short-term memory and peripheral blood Aβ_1-42 protein concentration in occupationally people who were exposed to 50 Hz power frequency electromagnetic field[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(11): 1326-1331. doi: 10.16462/j.cnki.zhjbkz.2022.11.015

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Study on the relationship between reduced short-term memory and peripheral blood Aβ_1-42 protein concentration in occupationally people who were exposed to 50 Hz power frequency electromagnetic field

doi: 10.16462/j.cnki.zhjbkz.2022.11.015

BIAN Hong-ying^{1
,
,},
ZHANG Yao²,
WANG Yan²,
DONG Yi-wen¹,
YE Meng^{1
,
,}

1.
Department of Occupational Epidemiology and Risk Assessment, National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing 100050, China
2.
Sichuan Electric Power Hospital, Industrial Sanitation Station, Chengdu 610011, China

Funds:

The Occupational Health and Poison Control Institute Youth Fund Project 2016PJ03

Occupational Health Risk Assessment and National Occupational Health Standard Development Project 131031109000160004

More Information

Corresponding author: BIAN Hong-ying, E-mail: bhy123@126.com; YE Meng, E-mail: yemeng@niohp.chinacdc.cn
Received Date: 2022-03-25
Rev Recd Date: 2022-08-02

Available Online: 2022-12-21

Publish Date: 2022-11-10

Abstract

Abstract

Objective To study the relationship between reduced short-term memory and peripheral blood Aβ_1-42 protein concentration induced by a 50 Hz power frequency electromagnetic field. Methods Fifty-one thermal power plant electrical operators were selected as the exposure group, and twenty-six administrative staffs of the same plant were selected as the control group. Both groups were tested for short-term memory, and the concentration of Aβ_1-42 protein in peripheral blood was measured simultaneously. The correlation between the two groups was compared. Results The 8 h time-weighted average intensity of the exposed group was 1.690 kV/m, and the magnetic field intensity was 4.578 μT. In the control group, the average electric field strength was 0.008 kV/m, and the magnetic field strength was 0.026 μT for 8h time-weighted average electric field intensity. The digit span score of the two groups in the exposed group was significantly lower than that in the control group (t=3.702, P < 0.001); the incidence of autonomic symptoms of insomnia (15.69%) and memory loss (21.57%) in the exposed group was significantly higher than the control group (all P < 0.05); the scores of three emotional state indicators in the exposed group were significantly lower than those in the control group, which incllding anger-hostility (t=2.239, P=0.028), fatigue-inert (t=2.024, P=0.047), and confusion-confusion (t=2.489, P=0.015); Aβ_1-42 protein concentration in peripheral blood (pg/mL) with significantly higher in exposure group when compared to the control group (t=-2.414, P=0.018). No correlation was found between digital span scores and changes in Aβ_1-42 protein concentration (r=-0.173, P=0.133). Conclusions 50 Hz power frequency electromagnetic field can cause short-term memory impairment in the occupational population and change the concentration of Aβ_1-42 protein in peripheral blood. However, the causal relationship between them needs further study.
- Power frequency electromagnetic field,
- Short-term memory impairment,
- Aβ_1-42 protein

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References(22)

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