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CN 34-1304/RISSN 1674-3679

Volume 26 Issue 11
Nov.  2022
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WANG Yuan-zhou, JIA Si-yue, ZHU Feng-cai, LI Jing-xin. Strategy for COVID-19 vaccination for patients with tuberculosis during the COVID-19 pandemic[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(11): 1344-1348. doi: 10.16462/j.cnki.zhjbkz.2022.11.018
Citation: WANG Yuan-zhou, JIA Si-yue, ZHU Feng-cai, LI Jing-xin. Strategy for COVID-19 vaccination for patients with tuberculosis during the COVID-19 pandemic[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(11): 1344-1348. doi: 10.16462/j.cnki.zhjbkz.2022.11.018

Strategy for COVID-19 vaccination for patients with tuberculosis during the COVID-19 pandemic

doi: 10.16462/j.cnki.zhjbkz.2022.11.018
Funds:

National Natural Science Foundation of China 82173584

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  • Corresponding author: LI Jing-xin, E-mail: jingxin42102209@126.com
  • Received Date: 2022-04-11
  • Rev Recd Date: 2022-07-03
  • Available Online: 2022-12-21
  • Publish Date: 2022-11-10
  • The pandemic of COVID-19 is still rampaging all over the world, so it is urgent to popularize vaccination. Meanwhile, pulmonary tuberculosis is one of the chronic infectious diseases with a high incidence in China. Since these diseases all occur in lung tissue, patients with TB and COVID-19 co-infection show more serious conditions and poorer treatment effects. However, we have limited knowledge about the protective efficacy, immunogenicity and safety of COVID-19 vaccine in patients with TB at present, with a lack of corresponding evidence-based medicine as well. Therefore, this paper reviews the pathogenesis and epidemiology of TB, discusses the immune status of patients with TB and summarizes the existing proposals for vaccination of patients with TB at home and abroad. Furthermore, we analyze the existing clinical trials in TB patients and other special populations, and finally discuss the strategy of vaccination for patients with TB during the COVID-19 pandemic and the necessity of clinical research on COVID-19 vaccines with target population of TB patients.
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