Advanced Search

CN 34-1304/RISSN 1674-3679

Volume 27 Issue 6
Jun.  2023
Turn off MathJax
Article Contents
XIONG Yan, YANG Jingyuan, ZHOU Quanxiang, QU Fang, CHEN Mingyan, YANG Xi, YANG Xing. Relationship between sleep quality and cognitive function and the mediating role of depression for older adults in the rural areas of Guizhou Province[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2023, 27(6): 645-649. doi: 10.16462/j.cnki.zhjbkz.2023.06.005
Citation: XIONG Yan, YANG Jingyuan, ZHOU Quanxiang, QU Fang, CHEN Mingyan, YANG Xi, YANG Xing. Relationship between sleep quality and cognitive function and the mediating role of depression for older adults in the rural areas of Guizhou Province[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2023, 27(6): 645-649. doi: 10.16462/j.cnki.zhjbkz.2023.06.005

Relationship between sleep quality and cognitive function and the mediating role of depression for older adults in the rural areas of Guizhou Province

doi: 10.16462/j.cnki.zhjbkz.2023.06.005
Funds:

National Natural Science Foundation of China 81760613

Science and Technology Fund Project of Guizhou Provincial Health Commission gzwjkj2019-1-224

More Information
  • Corresponding author: YANG Xing, E-mail: yangxgmc@163.com
  • Received Date: 2022-01-09
  • Rev Recd Date: 2022-04-28
  • Available Online: 2023-07-10
  • Publish Date: 2023-06-10
  •   Objective  This research seeks to examine how sleep quality influences the cognitive function of elderly individuals in rural areas of Guizhou Province, with a particular focus on the mediating role of depression.  Methods  We conducted a survey on 1 615 older adults living in rural areas of Guizhou Province using a general data questionnaire, the mini-mental state examination (MMSE), the Athens insomnia scale (AIS), and the patient health questionnaire-2 (PHQ-2). The structural equation model (SEM) was used to analyze the indirect effect of depression on the relationship between sleep quality and cognitive function.  Results  There were significant differences in cognitive function among older adults with different gender, ages, occupations, marital statuses, and educational levels (all P < 0.001). A direct association was identified between sleep quality and cognitive function (β=-0.061, 95% CI: -0.109-0.015), and depression displayed an indirect association between sleep quality and cognitive function (β=-0.113, 95% CI: -0.203-0.024). In addition, the mediating effect of depression (64.94%) on the correlation between sleep quality and cognitive function was greater than the direct effect of sleep quality on cognitive function (35.06%).  Conclusions  Sleep quality significantly affects the cognitive function of elderly individuals in rural areas of Guizhou Province. Additionally, depression plays a crucial mediating role in the relationship between sleep quality and cognitive function.
  • loading
  • [1]
    王振杰, 于海军, 唐婧, 等. 中国老年人认知障碍率的Meta分析[J]. 中国循证医学杂志, 2020, 20(11): 1295-1300. DOI: 10.7507/1672-2531.202006099.

    Wang ZJ, Yu HJ, Tang J, et al. Cognitive impairment rate of the elderly in China: a meta-analysis[J]. Chin J Evid Based Med, 2020, 20(11): 1295-1300. DOI: 10.7507/1672-2531.20200609.
    [2]
    Smith L, Shin JI, Jacob L, et al. Sleep problems and mild cognitive impairment among adults aged≥ 50 years from low-and middle-income countries[J]. Exp Gerontol, 2021, 154: 111513. DOI: 10.1016/j.exger.2021.111513.
    [3]
    Stojek MMK, Montoya AK, Drescher CF, et al. Fitness, sleep-disordered breathing, symptoms of depression, and cognition in inactive overweight children: mediation models[J]. Public Health Rep, 2017, 132(2_suppl): 65S-73S. DOI: 10.1177/0033354917731308.
    [4]
    熊风, 赖玉清, 涂嘉欣, 等. 中国老年人群睡眠障碍流行特征的Meta分析[J]. 中国循证医学杂志, 2019, 19(4): 398-403. DOI: 10.7507/1672-2531.201808151.

    Xiong F, Lai YQ, Tu JX, et al. Epidemiological characteristics of sleep disorders in the Chinese elderly: a meta-analysis[J]. Chin J Evid Based Med, 2019, 19(4): 398-403. DOI: 10.7507/1672-2531.201808151.
    [5]
    杨婷, 汪敬轩, 谢志豪, 等. 中国老年居民抑郁症状现状及其影响因素分析[J]. 现代预防医学, 2021, 48(19): 3461-3465, 3599.

    Yang T, Wang JX, Xie ZH, et al. Current status of depressive symptoms and their influencing factors among elderly Chinese residents[J]. Mod Prev Med, 2021, 48(19): 3461-3465, 3599.
    [6]
    郑培, 薛蓉. 睡眠对类淋巴系统清除β淀粉样蛋白的影响[J]. 中华老年心脑血管病杂志, 2019, 21(1): 100-102. DOI: 10.3969/j.issn.1009-0126.2019.01.026.

    Zheng P, Xue R. Effect of sleep on the clearance of β-amyloid by lymphoid system[J]. Chin J Geriatr Heart Brain Vessel Dis, 2019, 21(1): 100-102. DOI: 10.3969/j.issn.1009-0126.2019.01.026.
    [7]
    Mac Giollabhui N. Inflammation and depression: research designs to better understand the mechanistic relationships between depression, inflammation, cognitive dysfunction, and their shared risk factors[J]. Brain Behav Immun Health, 2021, 15: 100278. DOI: 10.1016/j.bbih.2021.100278.
    [8]
    Goldstone A, Javitz HS, Claudatos SA, et al. Sleep disturbance predicts depression symptoms in early adolescence: initial findings from the adolescent brain cognitive development study[J]. J Adolesc Health, 2020, 66(5): 567-574. DOI: 10.1016/j.jadohealth.2019.12.005.
    [9]
    周小炫, 谢敏, 陶静, 等. 简易智能精神状态检查量表的研究和应用[J]. 中国康复医学杂志, 2016, 31(6): 694-696, 706. DOI: 10.3969/j.issn.1001-1242.2016.06.019.

    Zhou XX, Xie M, Tao J, et al. Study and application of mini-mental state examination[J]. Chin J Rehabil Med, 2016, 31(6): 694-696, 706. DOI: 10.3969/j.issn.1001-1242.2016.06.019.
    [10]
    Soldatos CR, Dikeos DG, Paparrigopoulos TJ. Athens insomnia scale: validation of an instrument based on ICD-10 criteria[J]. J Psychosom Res, 2000, 48(6): 555-560. DOI: 10.1016/s0022-3999(00)00095-7.
    [11]
    Silverberg JI, Lee B, Lei D, et al. Measurement properties of patient health questionnaire 9 and patient health questionnaire 2 in adult patients with atopic dermatitis[J]. Dermatitis, 2021, 32(4): 225-231. DOI: 10.1097/DER.0000000000000653.
    [12]
    张骏, 宋瑞远, 苏明宏, 等. 安徽省合肥市农村人群睡眠质量与认知功能的相关性分析[J]. 中华疾病控制杂志, 2015, 19(8): 819-823. DOI: 10.16462/j.cnki.zhjbkz.2015.08.016.

    Zhang J, Song RY, Su MH, et al. Correlation analysis of sleep quality and cognitive function among the Hefei rural population in Anhui Province[J]. Chin J Dis Control Prev, 2015, 19(8): 819-823. DOI: 10.16462/j.cnki.zhjbkz.2015.08.016.
    [13]
    Xu Y, Wen H, Li J, et al. The relationship between sleep disorders, anxiety, depression, and cognitive function with restless legs syndrome (RLS) in the elderly[J]. Sleep Breath, 2022, 26(3): 1309-1318. DOI: 10.1007/s11325-021-02477-y.
    [14]
    Schmidt MH, Dekkers MPJ, Baillieul S, et al. Measuring sleep, wakefulness, and circadian functions in neurologic disorders[J]. Sleep Med Clin, 2021, 16(4): 661-671. DOI: 10.1016/j.jsmc.2021.08.005.
    [15]
    Rahmani M, Rahmani F, Rezaei N. The brain-derived neurotrophic factor: missing link between sleep deprivation, insomnia, and depression[J]. Neurochem Res, 2020, 45(2): 221-231. DOI: 10.1007/s11064-019-02914-1.
    [16]
    Zhao S, Wang X, Chen Z, et al. Sex differences in the association between symptom profiles and cognitive functioning in patients with depressive disorder[J]. J Affect Disord, 2021, 287: 1-7. DOI: 10.1016/j.jad.2021.03.020.
    [17]
    Fonseca E, Campos Blanco DM, Castro Vilanova MD, et al. Relationship between sleep quality and cognitive performance in patients with epilepsy[J]. Epilepsy Behav, 2021, 122: 108127. DOI: 10.1016/j.yebeh.2021.108127.
    [18]
    Song D, Zhou J, Ma J, et al. Sleep disturbance mediates the relationship between depressive symptoms and cognitive function in older adults with mild cognitive impairment[J]. Geriatr Nurs, 2021, 42(5): 1019-1023. DOI: 10.1016/j.gerinurse.2021.06.004.
    [19]
    Xu WQ, Lin LH, Ding KR, et al. The role of depression and anxiety in the relationship between poor sleep quality and subjective cognitive decline in Chinese elderly: exploring parallel, serial, and moderated mediation[J]. J Affect Disord, 2021, 294: 464-471. DOI: 10.1016/j.jad.2021.07.063.
    [20]
    Guan Q, Hu X, Ma N, et al. Sleep quality, depression, and cognitive function in non-demented older adults[J]. J Alzheimer's Dis, 2020, 76(4): 1637-1650. DOI: 10.3233/JAD-190990.
    [21]
    Akers KG, Chérasse Y, Fujita Y, et al. Concise review: regulatory influence of sleep and epigenetics on adult hippocampal neurogenesis and cognitive and emotional function[J]. Stem cells, 2018, 36(7): 969-976. DOI: 10.1002/stem.2815.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(1)  / Tables(4)

    Article Metrics

    Article views (177) PDF downloads(29) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return