Characteristics and risk factors of early death among newly diagnosed HIV/AIDS in China, 2011-2020

JIN Yichen; QIN Qianqian; CAI Chang; CHEN Fangfang; TANG Houlin

doi:10.16462/j.cnki.zhjbkz.2023.06.010

Volume 27 Issue 6

Jun. 2023

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JIN Yichen, QIN Qianqian, CAI Chang, CHEN Fangfang, TANG Houlin. Characteristics and risk factors of early death among newly diagnosed HIV/AIDS in China, 2011-2020[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2023, 27(6): 673-677. doi: 10.16462/j.cnki.zhjbkz.2023.06.010

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JIN Yichen, QIN Qianqian, CAI Chang, CHEN Fangfang, TANG Houlin. Characteristics and risk factors of early death among newly diagnosed HIV/AIDS in China, 2011-2020[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2023, 27(6): 673-677. doi: 10.16462/j.cnki.zhjbkz.2023.06.010

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Characteristics and risk factors of early death among newly diagnosed HIV/AIDS in China, 2011-2020

doi: 10.16462/j.cnki.zhjbkz.2023.06.010

Division of Epidemiology, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China

Funds:

National Natural Science Foundation of China 71874168

More Information

Corresponding author: TANG Houlin, E-mail: tanghl@Chinaaids.cn
Received Date: 2023-01-09
Rev Recd Date: 2023-04-21

Available Online: 2023-07-10

Publish Date: 2023-06-10

Abstract

Abstract

Objective To understand epidemiological characteristics, trends and related factors associated with early death (death within one year after diagnosis) among newly diagnosed HIV/AIDS in China, providing evidence for policy making to reduce mortality of HIV/AIDS. Methods Data between 2011 and 2020 on early death among newly diagnosed HIV/AIDS aged ≥15 years old were collected from China Information System for Disease Control and Prevention.Joinpoint regression model was adopted to analyze the trend of early mortality.Multivariate and multinominal logistic regression was performed to explore risk factors of early death among HIV/AIDS. Results Of newly diagnosed HIV/AIDS patients, 10.68% died within one year after diagnosis.The proportion of early death declined quickly between 2011 and 2015[annual percentage change annual percentage change (APC)(%, 95%CI)=-9.95(-11.29--8.59)].Multivariate logistic regression indicated that male[OR (95% CI)=1.60(1.57-1.63)], age ≥ 30 years old[30- < 45 years old: OR (95% CI)=1.89(1.83-1.95);45- < 60 years old: OR (95% CI)=2.73(2.64-2.81);≥60 years old: OR (95% CI)=4.39(4.25-4.53)], having a middle school education or lower[OR (95% CI)=1.59(1.55-1.63)], heterosexual[OR (95% CI)=1.81(1.76-1.86)]and inject drug[OR (95% CI)=1.86(1.77-1.96)]transmission, diagnosed by medical institutions[OR (95% CI)=3.33(3.23-3.43)], voluntary counseling and test[OR (95% CI)=2.13(2.06-2.20)], baseline CD4⁺T lymphocyte count lower than 200/mm³[OR (95% CI)=4.83(4.75-4.92)], and failure to initiate antiretroviral treatment within 30 days after diagnosis[OR (95% CI)=2.69(2.64-2.74)]increased the risk of early death.Multinominal logistic regression indicated that risk factors of early death remained consistent among HIV/AIDS who died within different time frames. Conclusions There is a high proportion of early death among HIV/AIDS patients in China.Intensified efforts to enhance HIV screening and promote timely initiation of ART are needed.Continued commitment to HIV prevention and treatment is essential to reduce HIV/AIDS mortality.
- HIV/AIDS,
- Death,
- Risk factors

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References(16)

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